Cttnbp2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Cttnbp2
cortactin binding protein 2
MGI:1353467

19 phenotypes from 3 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Cttnbp2^em1Yph/Cttnbp2⁺ C57BL/6-Cttnbp2^em1Yph	abnormal response to social novelty	J:300704
Cttnbp2^em1Yph/Cttnbp2⁺ C57BL/6-Cttnbp2^em1Yph	impaired learning	J:300704
Cttnbp2^em1Yph/Cttnbp2⁺ Tg(Thy1-YFP)HJrs/0 B6.Cg-Cttnbp2^em1Yph Tg(Thy1-YFP)HJrs	abnormal dendritic spine morphology	J:300704
Cttnbp2^em1Yph/Cttnbp2^em1Yph C57BL/6-Cttnbp2^em1Yph	abnormal postsynaptic density morphology	J:300704
	abnormal response to social novelty	J:300704
	abnormal social investigation	J:300704
	abnormal spatial reference memory	J:300704
	abnormal synapse morphology	J:300704
	abnormal synaptic vesicle number	J:300704
	decreased brain zinc level	J:300704
	decreased neuron number	J:300704
	increased anxiety-related response	J:300704
	increased locomotor activity	J:300704
Cttnbp2^em1Yph/Cttnbp2^em1Yph Tg(Thy1-YFP)HJrs/0 B6.Cg-Cttnbp2^em1Yph Tg(Thy1-YFP)HJrs	abnormal dendritic spine morphology	J:300704
	decreased dendritic spine density	J:300704
	decreased dendritic spine length	J:300704
Cttnbp2^em2Yph/Cttnbp2⁺ C57BL/6-Cttnbp2^em2Yph	abnormal response to social novelty	J:300704
	decreased brain zinc level	J:300704
	decreased vocalization	J:300704
Cttnbp2^em2Yph/Cttnbp2⁺ Tg(Thy1-YFP)HJrs/0 B6.Cg-Cttnbp2^em2Yph Tg(Thy1-YFP)HJrs	abnormal dendritic spine morphology	J:300704
	decreased dendritic spine density	J:300704
Cttnbp2^{tm1b(KOMP)Wtsi}/Cttnbp2^{tm1b(KOMP)Wtsi} C57BL/6N-Cttnbp2^{tm1b(KOMP)Wtsi}/Wtsi	decreased transitional stage T1 B cell number	J:211773
	increased grip strength	J:211773
	increased memory CD4-positive, CD25-positive, alpha-beta regulatory T cell number	J:211773
	increased plasma cell number	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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