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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Abcc9
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
MGI:1352630
34 phenotypes from 3 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Abcc9tm1.1Mcn/Abcc9tm1.1Mcn
Tg(Tagln-cre)1Her/0
involves: 129 * 129S1/Sv * 129X1/SvJ * C57BL/6J
abnormal fetal cardiomyocyte morphology J:216539
abnormal fetal cardiomyocyte physiology J:216539
abnormal mitochondrial physiology J:216539
abnormal mitochondrion morphology J:216539
cardiomyopathy J:216539
decreased cardiac muscle contractility J:216539
decreased fatty acid oxidation J:216539
decreased mitochondria size J:216539
decreased oxygen consumption J:216539
enlarged heart J:216539
normal homeostasis/metabolism phenotype J:216539
hypoxia J:216539
increased cellular sensitivity to hydrogen peroxide J:216539
increased heart weight J:216539
oxidative stress J:216539
postnatal lethality, complete penetrance J:216539
Abcc9tm1Cfb/Abcc9tm1Cfb
involves: CD-1
hypoglycemia J:71840
improved glucose tolerance J:71840
increased insulin sensitivity J:71840
increased muscle cell glucose uptake J:71840
premature death J:71840
slow postnatal weight gain J:71840
Abcc9tm1Cfb/Abcc9tm1Cfb
Not Specified
abnormal ST segment J:78066
abnormal systemic arterial blood pressure J:78066
abnormal vascular smooth muscle physiology J:78066
abnormal vasoconstriction J:78066
artery stenosis J:78066
hypertension J:78066
increased systemic arterial diastolic blood pressure J:78066
increased systemic arterial systolic blood pressure J:78066
premature death J:78066
Tg(CMV-Abcc9)1Ajo/?
either: (involves: BALB/c * CBA) or (involves: BALB/c * C57BL/6J * CBA)
abnormal myocardial fiber physiology J:111456
abnormal sarcolemma morphology J:111456
altered response to myocardial infarction J:111456
decreased myocardial infarction size J:111456

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
06/11/2019
MGI 6.14
The Jackson Laboratory