Cxcl10 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Cxcl10
C-X-C motif chemokine ligand 10
MGI:1352450

13 phenotypes from 1 allele in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Cxcl10^tm1Adl/Cxcl10^tm1Adl B6.129S4-Cxcl10^tm1Adl	abnormal cytokine secretion	J:120743
	CNS inflammation	J:87076
	increased susceptibility to experimental autoimmune encephalomyelitis	J:87076
	increased susceptibility to Herpesvirales infection	J:120743
Cxcl10^tm1Adl/Cxcl10^tm1Adl involves: 129S4/SvJae * 129X1/SvJ	decreased IgG2a level	J:75584
	decreased interferon-gamma secretion	J:75584
	decreased splenocyte proliferation	J:75584
	decreased susceptibility to type IV hypersensitivity reaction	J:75584
Cxcl10^tm1Adl/Cxcl10^tm1Adl involves: 129S4/SvJae * C57BL/6	abnormal interferon level	J:75584
	abnormal T cell physiology	J:75584
	decreased CD8-positive, alpha-beta T cell number	J:75584
	demyelination	J:75584
	increased susceptibility to Hepadnaviridae infection	J:75584

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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