Magel2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Magel2
MAGE family member L2
MGI:1351648

41 phenotypes from 3 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Magel2^em2(IMPC)H/Magel2^em2(IMPC)H C57BL/6NTac-Magel2^em2(IMPC)H/H	abnormal locomotor behavior	J:211773
	decreased circulating serum albumin level	J:211773
	decreased circulating total protein level	J:211773
Magel2^tm1.1Mus/Magel2⁺ B6.129S2-Magel2^tm1.1Mus	abnormal hypothalamus secretion	J:166548
	abnormal suckling behavior	J:166548
	absent gastric milk in neonates	J:166548
	decreased body weight	J:166548
	decreased circulating glucose level	J:166548
	normal nervous system phenotype	J:166548
	perinatal lethality, incomplete penetrance	J:166548
Magel2^tm1.1Mus/Magel2⁺ involves: 129S2/SvPas * C57BL/6J	perinatal lethality, incomplete penetrance	J:166548
Magel2^tm1Stw/Magel2⁺ C57BL/6-Magel2^tm1Stw	abnormal corpus luteum morphology	J:144836
	abnormal proestrus	J:144836
	decreased circulating testosterone level	J:144836
	decreased litter size	J:144836
	delayed estrous cycle	J:144836
	delayed vaginal opening	J:144836
	early reproductive senescence	J:144836
	impaired olfaction	J:144836
	maternal imprinting	J:144836
	postnatal lethality, incomplete penetrance	J:144836
	prolonged estrous cycle	J:144836
	pup cannibalization	J:144836
Magel2^tm1Stw/Magel2^tm1Stw C57BL/6-Magel2^tm1Stw	abnormal circadian behavior	J:125637
	abnormal locomotor circadian rhythm	J:125637
	decreased compensatory feeding amount	J:125637
	decreased locomotor activity	J:125637
	normal growth/size/body region phenotype	J:125637
	maternal imprinting	J:125637
	postnatal lethality, incomplete penetrance	J:125637
	reduced male fertility	J:125637
Magel2^tm1Stw/Magel2^tm1Stw C57BL/6-Magel2^tm1Stw/J	abnormal autophagy	J:233299
	decreased grip strength	J:233299
	decreased lean body mass	J:233299
	decreased locomotor activity	J:233299
	decreased skeletal muscle fiber size	J:233299
	decreased skeletal muscle weight	J:233299
	decreased vertical activity	J:233299
	increased body fat mass	J:233299
	increased skeletal muscle fiber size	J:233299
	obese	J:233299
	prenatal lethality, incomplete penetrance	J:233299
	normal respiratory system phenotype	J:233299
	scoliosis	J:233299
	skeletal muscle atrophy	J:233299

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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