Thoc5 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Thoc5
THO complex 5
MGI:1351333

15 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Tg(Mx1-cre)1Cgn/0 Thoc5^tm1Tate/Thoc5^tm1Tate involves: C57BL/6 * CBA	abnormal bone marrow cell physiology	J:169944
	abnormal lymphopoiesis	J:169944
	anemia	J:169944
	decreased bone marrow cell number	J:169944
	decreased common myeloid progenitor cell number	J:169944
	decreased erythrocyte cell number	J:169944
	decreased hematocrit	J:169944
	decreased hematopoietic stem cell number	J:169944
	decreased hemoglobin content	J:169944
	decreased leukocyte cell number	J:169944
	decreased spleen weight	J:169944
	pale liver	J:169944
	premature death	J:169944
	thrombocytopenia	J:169944
Thoc5^tm1.1Tate/Thoc5^tm1.1Tate involves: C57BL/6 * CBA * FVB/N	embryonic lethality between implantation and somite formation, complete penetrance	J:169944

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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