Sec23b Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Sec23b
SEC23 homolog B, COPII coat complex component
MGI:1350925

32 phenotypes from 4 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Sec23b^{Gt(AD0407)Wtsi}/Sec23b^{Gt(AD0407)Wtsi} 129S1.129P2-Sec23b^{Gt(AD0407)Wtsi}	abnormal suckling behavior	J:186391
	decreased birth weight	J:186391
	neonatal lethality, complete penetrance	J:186391
Sec23b^{Gt(AD0407)Wtsi}/Sec23b^{Gt(AD0407)Wtsi} B6J.129P2-Sec23b^{Gt(AD0407)Wtsi}	abnormal endocrine pancreas development	J:186391
	abnormal endocrine pancreas morphology	J:186391
	abnormal exocrine pancreas physiology	J:186391
	abnormal intestinal goblet cell morphology	J:186391
	abnormal intestine morphology	J:186391
	abnormal pancreas morphology	J:186391
	abnormal pancreatic acinar cell morphology	J:186391, J:237614
	abnormal pancreatic acinus morphology	J:186391
	abnormal Paneth cell morphology	J:186391
	abnormal salivary gland morphology	J:186391, J:237614
	abnormal stomach glandular epithelium morphology	J:186391
	abnormal sublingual gland morphology	J:186391
	abnormal submandibular gland morphology	J:186391
	abnormal suckling behavior	J:186391
	absent pancreatic acinar cell zymogen granule	J:186391
	decreased birth weight	J:186391
	decreased circulating glucose level	J:186391
	decreased pancreatic acinar cell number	J:186391
	decreased pancreatic alpha cell number	J:186391
	decreased pancreatic beta cell number	J:186391
	decreased pancreatic islet number	J:186391
	gastric gland degeneration	J:186391
	normal hematopoietic system phenotype	J:186391
	normal homeostasis/metabolism phenotype	J:237614
	increased apoptosis	J:186391
	nasal gland degeneration	J:186391
	neonatal lethality, complete penetrance	J:186391
	pancreas degeneration	J:186391
	pancreas inflammation	J:186391
	pancreatic acinar hypoplasia	J:186391
	salivary gland degeneration	J:186391
	small pancreas	J:186391
Sec23b^{Gt(AD0407)Wtsi}/Sec23b^{Gt(AD0407)Wtsi} involves: 129P2/OlaHsd	normal hematopoietic system phenotype	J:213188
Sec23b^{tm1a(EUCOMM)Wtsi}/Sec23b^{tm1a(EUCOMM)Wtsi} involves: C57BL/6J * C57BL/6N	gastric gland degeneration	J:186391
	nasal gland degeneration	J:186391
	neonatal lethality, complete penetrance	J:186391
	pancreas degeneration	J:186391
	salivary gland degeneration	J:186391
Sec23b^{tm1b(EUCOMM)Wtsi}/Sec23b^{tm1b(EUCOMM)Wtsi} involves: C57BL/6J * C57BL/6N * FVB/N	gastric gland degeneration	J:186391
	nasal gland degeneration	J:186391
	neonatal lethality, complete penetrance	J:186391
	pancreas degeneration	J:186391
	salivary gland degeneration	J:186391
Sec23b^{tm1d(EUCOMM)Wtsi}/Sec23b^{tm1d(EUCOMM)Wtsi} involves: C57BL/6 * C57BL/6N * FVB/N * SJL	normal hematopoietic system phenotype	J:213188

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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