Exo1 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Exo1
exonuclease 1
MGI:1349427

7 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Aicda^tm1Hon/Aicda^tm1Hon Exo1^tm1Wed/Exo1^tm1Wed Igh^tm4.1Mnz/Igh⁺ involves: C57BL/6 * CBA/JNCrlj * SJL	abnormal immunoglobulin heavy chain V(D)J recombination	J:194603
Aicda^tm1Hon/Aicda^tm1Hon Exo1^tm1Wed/Exo1^tm1Wed Igh^tm4.1Mnz/Igh⁺ Trp53bp1^tm1Jc/Trp53bp1^tm1Jc involves: 129 * C57BL/6 * CBA/JNCrlj * SJL	abnormal immunoglobulin heavy chain V(D)J recombination	J:194603
Exo1^tm2Wed/Exo1^tm2Wed Trp53^tm1Tyj/Trp53^tm1Tyj involves: 129S2/SvPas * C57BL/6	chromosomal instability	J:198719
	increased tumor incidence	J:198719
	premature death	J:198719
Exo1^tm3.1Wed/Exo1^tm3.1Wed Trp53^tm1Tyj/Trp53^tm1Tyj involves: 129S2/SvPas * C57BL/6	abnormal chromosome stability	J:198719
	increased lymphoma incidence	J:198719
	increased sarcoma incidence	J:198719
	premature death	J:198719

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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