75 phenotypes from 3 alleles in 8 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Foxm1tm1.1Rhc/Foxm1tm1.1Rhc B6.129X1-Foxm1tm1.1Rhc	abnormal fetal cardiomyocyte morphology	J:119481
	abnormal ventricle myocardium morphology	J:119481
	decreased fetal cardiomyocyte number	J:119481
	decreased fetal cardiomyocyte proliferation	J:119481
	decreased heart left ventricle size	J:119481
	dilated heart ventricle	J:119481
	increased fetal cardiomyocyte size	J:119481
	small heart	J:119481
	thick heart valve cusps	J:119481
	thick mitral valve cusps	J:119481
	ventricular hypoplasia	J:119481
Foxm1tm1.1Rhc/Foxm1tm1.1Rhc involves: 129X1/SvJ	abnormal cell cycle	J:94883
	abnormal hepatic cord morphology	J:94883
	abnormal hepatic vein morphology	J:94883
	abnormal hepatoblast morphology	J:94883
	abnormal intrahepatic bile duct morphology	J:94883
	abnormal liver sinusoid morphology	J:94883
	decreased hepatoblast number	J:94883
	hemorrhage	J:94883
	hydrops fetalis	J:94883
	increased myocardial fiber size	J:94883
	lethality throughout fetal growth and development, complete penetrance	J:94883
Foxm1tm1.1Rhc/Foxm1tm1.1Rhc involves: 129X1/SvJ * C57BL/6	abnormal capillary morphology	J:100263
	abnormal carotid artery morphology	J:100263
	abnormal lung development	J:100263
	abnormal lung vasculature morphology	J:100263
	abnormal pulmonary artery morphology	J:100263
	aortic hypertrophy	J:100263
	decreased mesenchymal cell proliferation involved in lung development	J:100263
	vascular smooth muscle hypertrophy	J:100263
Foxm1tm1Cle/Foxm1tm1Cle Not Specified	abnormal hepatocyte morphology	J:95612
	abnormal myocardial fiber morphology	J:95612
	myocardial fiber disarray	J:95612
	perinatal lethality	J:95612
	respiratory failure	J:95612
	thin myocardium	J:95612
Foxm1tm1Rhc/Foxm1tm1Rhc involves: 129X1/SvJ	increased hepatocellular carcinoma incidence	J:89472
	increased incidence of tumors by chemical induction	J:89472
Foxm1tm1Rhc/Foxm1tm1Rhc Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ involves: 129X1/SvJ * C57BL/6 * DBA	abnormal hepatocyte morphology	J:81015, J:89472
	abnormal liver regeneration	J:81015
	decreased incidence of tumors by chemical induction	J:89472
	decreased liver tumor incidence	J:89472
Foxm1tm1Rhc/Foxm1tm1Rhc Tg(Alb1-cre)1Khk/0 involves: 129X1/SvJ * C57BL/6 * SJL	abnormal cell cycle	J:94883
	abnormal hepatic cord morphology	J:94883
	abnormal hepatic vein morphology	J:94883
	abnormal hepatoblast morphology	J:94883
	abnormal intrahepatic bile duct morphology	J:94883
	abnormal liver sinusoid morphology	J:94883
	decreased hepatoblast number	J:94883
	lethality throughout fetal growth and development, incomplete penetrance	J:94883
Foxm1tm1Rhc/Foxm1tm1Rhc Tg(Pdx1-cre)89.1Dam/0 involves: 129X1/SvJ * C57BL/6 * CBA	abnormal exocrine pancreas morphology	J:111026
	abnormal glucose homeostasis	J:111026
	abnormal insulin secretion	J:111026
	abnormal pancreatic beta cell morphology	J:111026
	abnormal pancreatic islet morphology	J:111026
	decreased pancreas weight	J:111026
	decreased pancreatic beta cell mass	J:111026
	decreased pancreatic beta cell number	J:111026
	decreased pancreatic beta cell proliferation	J:111026
	impaired glucose tolerance	J:111026
	increased pancreatic alpha cell number	J:111026
	pancreas cyst	J:111026
	pancreas necrosis	J:111026
	small pancreatic islets	J:111026
Foxm1tm1Rhc/Foxm1tm1Rhc Tg(SFTPC-rtTA)5Jaw/0 Tg(tetO-cre)1Jaw/0 involves: 129 * 129X1/SvJ * C57BL/6	abnormal lung development	J:142246
	abnormal lung saccule morphology	J:142246
	abnormal pulmonary alveolus epithelial cell morphology	J:142246
	abnormal respiratory conducting tube morphology	J:142246
	abnormal type II pneumocyte morphology	J:142246
	atelectasis	J:142246
	decreased surfactant secretion	J:142246
	decreased type I pneumocyte number	J:142246
	neonatal lethality, incomplete penetrance	J:142246
	pulmonary hyaline membrane formation	J:142246
	pulmonary vascular congestion	J:142246
	respiratory distress	J:142246
	respiratory failure	J:142246
	normal respiratory system phenotype	J:142246
	small alveolar lamellar bodies	J:142246
	small lung saccule	J:142246
	thick lung-associated mesenchyme	J:142246
Foxm1tm1Rhc/Foxm1tm1Rhc Tg(Tek-cre)1Ywa/0 involves: 129X1/SvJ * C57BL/6 * SJL	abnormal lung vasculature morphology	J:119481
	normal cardiovascular system phenotype	J:119481
	increased incidence of tumors by chemical induction	J:167773
	increased lung adenoma incidence	J:167773
	lethality during fetal growth through weaning, incomplete penetrance	J:119481
	lung inflammation	J:167773