Foxa1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Foxa1
forkhead box A1
MGI:1347472

19 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Foxa1^tm1Gsc/Foxa1⁺ involves: 129P2/OlaHsd	abnormal branching of the mammary ductal tree	J:161401
Foxa1^tm1Gsc/Foxa1⁺ involves: 129P2/OlaHsd	increased mammary gland apoptosis	J:161401
Foxa1^tm1Gsc/Foxa1^tm1Gsc involves: 129P2/OlaHsd	abnormal branching of the mammary ductal tree	J:161401
Foxa1^tm1Gsc/Foxa1^tm1Gsc involves: 129P2/OlaHsd * C57BL/6	abnormal adrenal gland secretion	J:53312
	abnormal circulating insulin level	J:53312
	decreased circulating glucagon level	J:53312
	hypoglycemia	J:53312
	postnatal growth retardation	J:53312
	postnatal lethality, complete penetrance	J:53312
Foxa1^tm1Stf/Foxa1⁺ Not Specified	decreased circulating HDL cholesterol level	J:138581
Foxa1^tm1Stf/Foxa1^tm1Stf Not Specified	abnormal glucose homeostasis	J:57493
	decreased body weight	J:57493
	decreased circulating glucagon level	J:57493
	decreased circulating insulin level	J:57493
	decreased circulating triglyceride level	J:57493
	decreased insulin secretion	J:57493
	normal endocrine/exocrine gland phenotype	J:57493
	normal homeostasis/metabolism phenotype	J:57493
	hypoglycemia	J:57493
	impaired glucose tolerance	J:57493
	increased circulating cortisol level	J:57493
	increased circulating growth hormone level	J:57493
	postnatal growth retardation	J:57493
	postnatal lethality, complete penetrance	J:57493

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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