Spry4 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Spry4
sprouty RTK signaling antagonist 4
MGI:1345144

19 phenotypes from 4 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Spry4^{Gt(pT1ATGBetageo)1Ruiz}/Spry4^{Gt(pT1ATGBetageo)1Ruiz} involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal limb morphology	J:85162
Spry4^tm1.2Mrt/Spry4^tm1.2Mrt involves: 129P2/OlaHsd * C57BL/6 * FVB/N * SJL	supernumerary teeth	J:119280
Spry4^tm1Ayos/Spry4^tm1Ayos B6.Cg-Spry4^tm1Ayos	abnormal incisor morphology	J:116506
	abnormal mandible morphology	J:116506
	decreased body weight	J:116506
	malocclusion	J:116506
	polysyndactyly	J:116506
	postnatal growth retardation	J:116506
	postnatal lethality, incomplete penetrance	J:116506
	normal respiratory system phenotype	J:116506
Spry4^{tm1b(KOMP)Mbp}/Spry4^{tm1b(KOMP)Mbp} C57BL/6N-Spry4^{tm1b(KOMP)Mbp}/Kmpc	abnormal cornea morphology	J:211773
	abnormal digit morphology	J:211773
	brachydactyly	J:211773
	corneal opacity	J:211773
	decreased fasting circulating glucose level	J:211773
	decreased grip strength	J:211773
	hyperactivity	J:211773
	narrow eye opening	J:211773
	short tibia	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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