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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Pbx2
pre B cell leukemia homeobox 2
MGI:1341793
21 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Gt(ROSA)26Sortm2(Wnt1/GFP)Amc/Gt(ROSA)26Sor+
Pbx1tm1Koss/Pbx1tm1Koss
Pbx2tm1Mlc/Pbx2+
Tg(Tcfap2a-cre)1Will/0
involves: 129P2/OlaHsd * 129S/Sv * 129X1/SvJ 		normal craniofacial phenotype J:178316
Pbx1tm1Koss/Pbx1tm1Koss
Pbx2tm1Mlc/Pbx2+
Foxg1tm1(cre)Skm/Foxg1+
involves: 129P2/OlaHsd * 129S/Sv 		abnormal maxillary shelf morphology J:178316
abnormal nasal capsule morphology J:178316
absent premaxilla J:178316
bilateral cleft upper lip J:178316
cleft palate J:178316
neonatal lethality, complete penetrance J:178316
Pbx1tm1Koss/Pbx1tm1Koss
Pbx2tm1Mlc/Pbx2+
H2az2Tg(Wnt1-cre)11Rth/H2az2+
involves: 129P2/OlaHsd * 129S/Sv * C57BL/6J * CBA/J 		cleft palate J:178316
normal nervous system phenotype J:178316
postnatal lethality, complete penetrance J:178316
Pbx1tm1Koss/Pbx1tm1Koss
Pbx2tm1Mlc/Pbx2+
Nkx2-5tm2(cre)Rph/Nkx2-5+
involves: 129P2/OlaHsd * 129S/Sv * 129S1/Sv 		abnormal spleen morphology J:184521
spleen hypoplasia J:184521
Pbx1tm1Koss/Pbx1tm1Koss
Pbx2tm1Mlc/Pbx2+
Tg(Tcfap2a-cre)1Will/0
involves: 129P2/OlaHsd * 129S/Sv 		cleft palate J:178316
cleft upper lip J:178316
Pbx1tm1Koss/Pbx1tm1Koss
Pbx2tm1Mlc/Pbx2tm1Mlc
Foxg1tm1(cre)Skm/Foxg1+
involves: 129P2/OlaHsd * 129S/Sv 		bilateral cleft upper lip J:178316
decreased apoptosis J:178316
Pbx1tm1Mlc/Pbx1+
Pbx2tm1Mlc/Pbx2+
Pbx3tm1Mlc/Pbx3+
involves: 129S6/SvEvTac 		cleft palate J:178316
neonatal lethality, complete penetrance J:178316
Pbx1tm1Mlc/Pbx1tm1Mlc
Pbx2tm1Mlc/Pbx2+
involves: 129S6/SvEvTac 		abnormal lateral nasal prominence morphology J:178316
abnormal maxillary prominence morphology J:178316
abnormal medial nasal prominence morphology J:178316
bilateral cleft upper lip J:178316
cleft upper lip J:178316
edema J:178316
micrognathia J:178316
small snout J:178316
tongue hypoplasia J:178316
unilateral cleft upper lip J:178316
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory