Fkbp8 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Fkbp8
FK506 binding protein 8
MGI:1341070

39 phenotypes from 3 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Fkbp8^{Gt(OST287985)Lex}/Fkbp8^{Gt(OST287985)Lex} involves: 129S5/SvEvBrd * C57BL/6	abnormal dorsal-ventral axis patterning	J:132031
	abnormal neural tube morphology	J:132031
	abnormal spinal cord morphology	J:132031
	abnormal vertebral arch development	J:132031
	disorganized dorsal root ganglion	J:132031
	hindlimb paralysis	J:132031
	increased neural tube apoptosis	J:132031
	increased spinal cord size	J:132031
	short vertebral column	J:132031
	slow postnatal weight gain	J:132031
	spina bifida	J:132031
	vertebral fusion	J:132031
Fkbp8^tm1Kei/Fkbp8^tm1Kei involves: 129P2/OlaHsd	abnormal cell physiology	J:132541
Fkbp8^tm1Kei/Fkbp8^tm1Kei involves: 129P2/OlaHsd * C57BL/6J	abnormal brain morphology	J:132961
	abnormal cerebellum morphology	J:132961
	abnormal cerebral hemisphere morphology	J:132961
	abnormal dorsal root ganglion morphology	J:132961
	abnormal embryonic neuroepithelium morphology	J:132961
	abnormal embryonic/fetal subventricular zone morphology	J:132961
	abnormal limb morphology	J:132961
	abnormal lumbar vertebrae morphology	J:132961
	abnormal neural tube morphology	J:132961
	abnormal neuron differentiation	J:132961
	abnormal rib morphology	J:132961
	abnormal spinal cord morphology	J:132961
	abnormal suckling behavior	J:132961
	abnormal thalamus morphology	J:132961
	abnormal vertebral arch morphology	J:132961
	clubfoot	J:132961
	curly tail	J:132961
	cyanosis	J:132961
	decreased body size	J:132961
	dehydration	J:132961
	exencephaly	J:132961
	neonatal lethality, complete penetrance	J:132961
	respiratory distress	J:132961
	scoliosis	J:132961
	spina bifida	J:132961
Fkbp8^tm1Tili/Fkbp8^tm1Tili involves: C57BL/6	abnormal dorsal-ventral axis patterning	J:89364
	abnormal neural tube morphology	J:89364
	anophthalmia	J:89364
	embryonic lethality during organogenesis, complete penetrance	J:89364
	microphthalmia	J:89364
	small dorsal root ganglion	J:89364
Fkbp8^tm1Tili/Fkbp8^tm1Tili Not Specified	embryonic lethality during organogenesis, complete penetrance	J:132961

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/16/2024 MGI 6.23