Ankfy1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ankfy1
ankyrin repeat and FYVE domain containing 1
MGI:1337008

26 phenotypes from 2 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ankfy1^{Gt(RRE069)Byg}/Ankfy1⁺ B6.129P2-Ankfy1^{Gt(RRE069)Byg}	abnormal motor capabilities/coordination/movement	J:250135
	abnormal Purkinje cell dendrite morphology	J:250135
	ataxia	J:250135
	decreased body weight	J:250135
	decreased brain size	J:250135
	gliosis	J:250135
	hindlimb paralysis	J:250135
	impaired coordination	J:250135
	increased brain apoptosis	J:250135
	kyphosis	J:250135
	limb grasping	J:250135
	Purkinje cell degeneration	J:250135
	short stride length	J:250135
	small cerebellum	J:250135
	spasticity	J:250135
	tremors	J:250135
Ankfy1^{Gt(RRE069)Byg}/Ankfy1^{Gt(RRE069)Byg} B6.129P2-Ankfy1^{Gt(RRE069)Byg}	embryonic lethality, complete penetrance	J:250135, J:251778
Ankfy1^{Gt(RRE069)Byg}/Ankfy1^{Gt(RRE069)Byg} C.129P2(B6)-Ankfy1^{Gt(RRE069)Byg}	embryonic lethality, complete penetrance	J:251778
Ankfy1^{Gt(RRE069)Byg}/Ankfy1^{Gt(RRE069)Byg} involves: 129P2/OlaHsd * C57BL/6	embryonic lethality, incomplete penetrance	J:251778
Ankfy1^{tm1b(KOMP)Mbp}/Ankfy1⁺ C57BL/6N-Ankfy1^{tm1b(KOMP)Mbp}/Tcp	abnormal heart morphology	J:211773
	enlarged heart	J:211773
	hydrometra	J:211773
	increased monocyte cell number	J:211773
	small superior vagus ganglion	J:211773
Ankfy1^{tm1b(KOMP)Mbp}/Ankfy1^{tm1b(KOMP)Mbp} C57BL/6N-Ankfy1^{tm1b(KOMP)Mbp}/Tcp	embryonic lethality prior to organogenesis	J:211773
	embryonic lethality prior to tooth bud stage	J:211773
	preweaning lethality, complete penetrance	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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