Mbd3 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Mbd3
methyl-CpG binding domain protein 3
MGI:1333812

5 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Mbd3^tm1Bh/Mbd3^tm1Bh involves: 129P2/OlaHsd * C57BL/6	embryonic lethality between implantation and somite formation, complete penetrance	J:68356
Mbd3^tm2Bh/Mbd3^tm2Bh Tg(Vil1-cre)20Syr/0 involves: 129P2/OlaHsd * C57BL/6 * DBA/2	abnormal small intestinal crypt cell proliferation	J:167984
	increased incidence of tumors by chemical induction	J:167984
	increased susceptibility to induced colitis	J:167984
	increased tumor growth/size	J:167984

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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