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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Dyrk1a
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1a
MGI:1330299
24 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background
Annotated Term Reference
Dp(16Lipi-Zbtb21)1Yey/0
Dyrk1aGt(XQ0369)Wtsi/Dyrk1a+
involves: 129/Sv * 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6
decreased exploration in new environment J:224899
impaired contextual conditioning behavior J:224899
Tg(CEPHY152F7)12Hgc/0
(C57BL/6 x FVB/N)F1
abnormal spatial learning J:128896
hypoactivity J:128896
normal nervous system phenotype J:128896
Tg(CEPHY152F7)12Hgc/0
FVB-Tg(CEPHY152F7)12Hgc
abnormal emotion/affect behavior J:128896
abnormal reflex J:128896
Tg(CEPHY152F7)57Hgc/0
(C57BL/6 x FVB/N)F1
abnormal spatial learning J:128896
hypoactivity J:128896
normal nervous system phenotype J:128896
Tg(CEPHY152F7)57Hgc/0
FVB-Tg(CEPHY152F7)57Hgc
abnormal emotion/affect behavior J:128896
abnormal reflex J:128896
Tg(DYRK1A)36Wjs/0
involves: C57BL/6NCrjBgi
abnormal long term depression J:111293
abnormal motor coordination/balance J:111293
abnormal neuron proliferation J:166796
abnormal neuronal precursor proliferation J:166796
abnormal spatial reference memory J:111293
enhanced long term potentiation J:111293
impaired synaptic plasticity J:111293
increased brain weight J:111293
reduced long term depression J:111293
Tg(MT1A-Dyrk1a)33Xest/0
involves: C57BL/6 * SJL
abnormal spatial learning J:71821
abnormal spatial reference memory J:71821
Tg(MT1A-Dyrk1a)#Xest/0
involves: C57BL/6 * SJL
abnormal behavior J:71821
abnormal gait J:71821
abnormal locomotor activation J:71821
abnormal locomotor behavior J:71821
abnormal paired-pulse inhibition J:140647
decreased anxiety-related response J:71821
hyperactivity J:71821, J:140647
impaired coordination J:71821, J:140647

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/12/2018
MGI 6.12
The Jackson Laboratory