Sptbn2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Sptbn2
spectrin beta, non-erythrocytic 2
MGI:1313261

20 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Sptbn2^Gt(XK442)Byg/Sptbn2⁺ involves: 129P2/OlaHsd * C57BL/6J	impaired coordination	J:158494
Sptbn2^Gt(XK442)Byg/Sptbn2^Gt(XK442)Byg involves: 129P2/OlaHsd * C57BL/6J	abnormal cerebellar molecular layer	J:158494
	abnormal Purkinje cell dendrite morphology	J:158494
	abnormal Purkinje cell morphology	J:158494
	ataxia	J:158494
	clonic seizures	J:158494
	increased body weight	J:158494
	thin cerebellar molecular layer	J:158494
Sptbn2^{tm1b(EUCOMM)Hmgu}/Sptbn2^{tm1b(EUCOMM)Hmgu} C57BL/6N-Sptbn2^{tm1b(EUCOMM)Hmgu}/H	decreased hemoglobin content	J:211773
	increased circulating creatine kinase level	J:211773
	increased circulating phosphate level	J:211773
	short tibia	J:211773
Sptbn2^tm1Mjac/Sptbn2⁺ involves: 129P2/OlaHsd	normal behavior/neurological phenotype	J:163169
Sptbn2^tm1Mjac/Sptbn2⁺ involves: 129P2/OlaHsd	normal nervous system phenotype	J:163169
Sptbn2^tm1Mjac/Sptbn2^tm1Mjac B6.129P2-Sptbn2^tm1Mjac	abnormal gait	J:159622
	abnormal nervous system electrophysiology	J:159622
	ataxia	J:159622
	impaired balance	J:159622
	impaired coordination	J:159622
	increased excitatory postsynaptic current amplitude	J:159622
	Purkinje cell degeneration	J:159622
	tremors	J:159622

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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