Axin2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Axin2
axin 2
MGI:1270862

41 phenotypes from 5 alleles in 7 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Axin2^canp/Axin2^canp C3.B6-Axin2^canp	abnormal heart morphology	J:171894
	abnormal neural plate morphology	J:171894
	abnormal primitive streak morphology	J:171894
	abnormal tail development	J:171894
	abnormal tail morphology	J:171894
	cardia bifida	J:171894
	embryonic growth arrest	J:171894
	embryonic lethality during organogenesis, incomplete penetrance	J:171894
	exencephaly	J:171894
	open neural tube	J:171894
Axin2^canp/Axin2^tm1Wbm involves: 129P2/OlaHsd * C3H * C57BL/6J	no abnormal phenotype detected	J:171894
Axin2^em1Fstl/Axin2⁺ involves: C57BL/6J * C57BL/6JIcoCrlLumc * CBA/J	curly tail	J:252680
	postnatal growth retardation	J:252680
Axin2^em1Fstl/Axin2^em1Fstl involves: C57BL/6J * C57BL/6JIcoCrlLumc * CBA/J	curly tail	J:252680
	postnatal growth retardation	J:252680
Axin2^M1J/Axin2⁺ C57BL/6J-Axin2^M1J/GrsrJ	kinked tail	J:223644
Axin2^M1J/Axin2⁺ C57BL/6J-Axin2^M1J/GrsrJ	prenatal lethality, incomplete penetrance	J:223644
Axin2^M1J/Axin2⁺ involves: C57BL/6J * FVB/NJ	kinked tail	J:223644
Axin2^M1J/Axin2⁺ involves: C57BL/6J * FVB/NJ	prenatal lethality, incomplete penetrance	J:223644
Axin2^{tm1b(KOMP)Wtsi}/Axin2⁺ C57BL/6N-Axin2^{tm1b(KOMP)Wtsi}/Bay	abnormal skin coloration	J:211773
	unresponsive to tactile stimuli	J:211773
Axin2^{tm1b(KOMP)Wtsi}/Axin2^{tm1b(KOMP)Wtsi} C57BL/6N-Axin2^{tm1b(KOMP)Wtsi}/Bay	abnormal body wall morphology	J:211773
	abnormal embryo development	J:211773
	abnormal embryo size	J:211773
	abnormal eyelid fusion	J:211773
	abnormal facial morphology	J:211773
	abnormal head shape	J:211773
	abnormal limb morphology	J:211773
	anophthalmia	J:211773
	microphthalmia	J:211773
	polydactyly	J:211773
	preweaning lethality, complete penetrance	J:211773
	protruding tongue	J:211773
	unresponsive to tactile stimuli	J:211773
Axin2^tm1Wbm/Axin2^tm1Wbm involves: 129P2/OlaHsd * C57BL/6	abnormal cranium morphology	J:98523
	abnormal eye morphology	J:98523
	abnormal neurocranium morphology	J:98523
	abnormal osteoblast physiology	J:98523
	abnormal skeleton development	J:98523
	absent jugum limitans	J:98523
	decreased cranium height	J:98523
	enhanced osteoblast differentiation	J:98523
	increased osteoblast proliferation	J:98523
	premature intramembranous bone ossification	J:98523
	premature metopic suture closure	J:98523
	shortened head	J:98523

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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