Zfp106 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Zfp106
zinc finger protein 106
MGI:1270153

57 phenotypes from 5 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Tg(Mnx1-Zfp106,-EGFP)1Blk/0 Zfp106^{tm1b(KOMP)Wtsi}/Zfp106^{tm1b(KOMP)Wtsi} involves: C57BL/6N	abnormal body weight	J:241305
	abnormal motor capabilities/coordination/movement	J:241305
	abnormal motor neuron morphology	J:241305
	abnormal muscle fiber morphology	J:241305
Tg(Mnx1-Zfp106,-EGFP)2Blk/0 Zfp106^{tm1b(KOMP)Wtsi}/Zfp106^{tm1b(KOMP)Wtsi} involves: C57BL/6N	abnormal body weight	J:241305
	abnormal motor capabilities/coordination/movement	J:241305
	abnormal motor neuron morphology	J:241305
	abnormal muscle fiber morphology	J:241305
Zfp106^em1Blk/Zfp106^em1Blk Not Specified	abnormal physical strength	J:241305
	abnormal skeletal muscle morphology	J:241305
	cachexia	J:241305
	decreased grip strength	J:241305
	decreased motor neuron number	J:241305
	skeletal muscle fiber atrophy	J:241305
	skeletal muscle fiber degeneration	J:241305
Zfp106^{tm1a(KOMP)Wtsi}/Zfp106⁺ B6JTyr;B6N-Zfp106^{tm1a(KOMP)Wtsi}/Wtsi	decreased mean corpuscular hemoglobin	J:165965
	increased circulating calcium level	J:175295
Zfp106^{tm1a(KOMP)Wtsi}/Zfp106^{tm1a(KOMP)Wtsi} B6JTyr;B6N-Zfp106^{tm1a(KOMP)Wtsi}/Wtsi	abnormal external male genitalia morphology	J:175295
	abnormal gait	J:165965
	decreased body weight	J:165965
	increased thermal nociceptive threshold	J:165965
Zfp106^{tm1a(KOMP)Wtsi}/Zfp106^{tm1a(KOMP)Wtsi} involves: C57BL/6Brd * C57BL/6Dnk * C57BL/6N	abnormal axon morphology	J:229162
	abnormal gait	J:229162
	abnormal gastrocnemius morphology	J:229162
	abnormal lumbar dorsal root ganglion morphology	J:229162
	abnormal mitochondrial ATP synthesis coupled electron transport	J:229162
	abnormal mitochondrial physiology	J:229162
	abnormal muscle electrophysiology	J:229162
	abnormal muscle physiology	J:229162
	abnormal redox activity	J:229162
	abnormal skeletal muscle fiber type ratio	J:229162
	abnormal soleus morphology	J:229162
	abnormal spinal cord morphology	J:229162
	astrocytosis	J:229162
	axon degeneration	J:229162
	centrally nucleated skeletal muscle fibers	J:229162
	chromatolysis	J:229162
	decreased gastrocnemius weight	J:229162
	decreased grip strength	J:229162
	decreased locomotor activity	J:229162
	decreased skeletal muscle fiber number	J:229162
	decreased soleus weight	J:229162
	decreased tibialis anterior weight	J:229162
	gliosis	J:229162
	impaired coordination	J:229162
	impaired limb coordination	J:229162
	increased spinal cord apoptosis	J:229162
	increased variability of skeletal muscle fiber size	J:229162
	kyphosis	J:229162
	limb grasping	J:229162
	microgliosis	J:229162
	motor neuron degeneration	J:229162
	normal nervous system phenotype	J:229162
	neurodegeneration	J:229162
	positive geotaxis	J:229162
	premature death	J:229162
	skeletal muscle atrophy	J:229162
	skeletal muscle fiber atrophy	J:229162
	skeletal muscle fibrosis	J:229162
	small dorsal root ganglion	J:229162
	small L4 dorsal root ganglion	J:229162
	small L5 dorsal root ganglion	J:229162
	tremors	J:229162
	weight loss	J:229162
Zfp106^{tm1b(KOMP)Wtsi}/Zfp106^{tm1b(KOMP)Wtsi} involves: C57BL/6N	abnormal physical strength	J:241305
	abnormal skeletal muscle morphology	J:241305
	cachexia	J:241305
	decreased grip strength	J:241305
	decreased motor neuron number	J:241305
	skeletal muscle fiber atrophy	J:241305
	skeletal muscle fiber degeneration	J:241305

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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