Myoc Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Myoc
myocilin
MGI:1202864

12 phenotypes from 4 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Myoc^tm1.1Rjo/Myoc^tm1.1Rjo involves: 129S7/SvEvBrd * C57BL/6	no abnormal phenotype detected	J:72628
Myoc^tm1Rjo/Myoc^tm1Rjo either: 129S7/SvEvBrd or (involves: 129S7/SvEvBrd * C57BL/6)	no abnormal phenotype detected	J:72628
Myoc^tm2.1Rjo/Myoc^tm2.1Rjo either: (involves: 129S7/SvEvBrd * AKR/J * C57BL/6J) or (involves: 129S7/SvEvBrd * BALB/c * C57BL/6J)	normal vision/eye phenotype	J:115971
Myoc^tm2.1Rjo/Myoc^tm2.1Rjo involves: 129S7/SvEvBrd * C57BL/6J	abnormal intraocular pressure	J:115971
	normal vision/eye phenotype	J:115971
Myoc^tm2.1Rjo/Myoc^tm2.1Rjo involves: 129S7/SvEvBrd * C57BL/6J * CBA/CaJ	normal vision/eye phenotype	J:115971
Tg(MyocY423H)#Sit/0 B6.FVB-Tg(MyocY423H)#Sit	abnormal canal of Schlemm morphology	J:116124
	abnormal retina inner plexiform layer morphology	J:116124
	abnormal retina neuronal layer morphology	J:116124
	abnormal trabecular meshwork morphology	J:116124
	astrocytosis	J:116124
	axon degeneration	J:116124
	ocular hypertension	J:116124
	optic nerve degeneration	J:116124
	retina ganglion cell degeneration	J:116124

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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