Klrk1 Phenotype Annotations

About Help FAQ

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Klrk1
killer cell lectin-like receptor subfamily K, member 1
MGI:1196250

13 phenotypes from 4 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Klrk1^em1(IMPC)Mbp/Klrk1^em1(IMPC)Mbp C57BL/6NCrl-Klrk1^em1(IMPC)Mbp/MbpMmucd	abnormal skin morphology	J:211773
	abnormal spleen morphology	J:211773
	enlarged spleen	J:211773
Klrk1^tm1.1Bpol/Klrk1^tm1.1Bpol C57BL/6-Klrk1^tm1.1Bpol	abnormal NK cell differentiation	J:151878
	abnormal NK cell physiology	J:151878
	decreased B cell number	J:151878
	decreased susceptibility to Herpesvirales infection	J:151878
	decreased susceptibility to Herpesvirales infection induced morbidity/mortality	J:151878
	decreased T cell number	J:151878
	impaired natural killer cell mediated cytotoxicity	J:151878
	increased interferon-gamma secretion	J:151878
	spleen hypoplasia	J:151878
Klrk1^tm1Dhr/Klrk1^tm1Dhr B6.Cg-Klrk1^tm1Dhr/J	increased natural killer cell mediated cytotoxicity	J:221188
Klrk1^tm1Dhr/Klrk1^tm1Dhr involves: C57BL/6 * CD-1	impaired natural killer cell mediated cytotoxicity	J:134509
Klrk1^tm2.1Bpol/Klrk1^tm2.1Bpol Not Specified	abnormal NK cell differentiation	J:215590
Klrk1^tm2.1Bpol/Klrk1^tm2.1Bpol Not Specified	decreased susceptibility to Herpesvirales infection	J:215590

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/16/2024 MGI 6.23