Dhx15 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Dhx15
DEAH-box helicase 15
MGI:1099786

16 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Dhx15^em1(IMPC)Tcp/Dhx15⁺ C57BL/6NCrl-Dhx15^em1(IMPC)Tcp/Tcp	abnormal lens morphology	J:211773
	decreased hematocrit	J:211773
	decreased mean corpuscular volume	J:211773
	decreased prepulse inhibition	J:211773
	increased erythrocyte cell number	J:211773
	increased mean corpuscular hemoglobin concentration	J:211773
	shortened QT interval	J:211773
Dhx15^em1(IMPC)Tcp/Dhx15^em1(IMPC)Tcp C57BL/6NCrl-Dhx15^em1(IMPC)Tcp/Tcp	preweaning lethality, complete penetrance	J:211773
Dhx15^{tm1c(EUCOMM)Wtsi}/Dhx15^{tm1c(EUCOMM)Wtsi} Cd19^tm1(cre)Cgn/Cd19⁺ involves: 129P2/OlaHsd * C3H * C57BL/6N	abnormal B cell differentiation	J:284624
	decreased B cell number	J:284624
	decreased B cell proliferation	J:284624
	decreased pre-B cell number	J:284624
	decreased spleen weight	J:284624
	spleen hypoplasia	J:284624
Dhx15^{tm1c(EUCOMM)Wtsi}/Dhx15^{tm1c(EUCOMM)Wtsi} Tg(Cd4-cre)1Cwi/0 involves: C3H * C57BL/6N * DBA/2	decreased CD4-positive, alpha-beta T cell number	J:284624
	decreased CD8-positive, alpha-beta T cell number	J:284624

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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