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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Cd81
CD81 antigen
MGI:1096398
33 phenotypes from 3 alleles in 7 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Cd81tm1Geha/Cd81tm1Geha
involves: 129S4/SvJae * C57BL/6 		abnormal B cell morphology J:43975
abnormal nucleus accumbens morphology J:69590
decreased B-1 B cell number J:43975
decreased B-1a cell number J:43975
decreased locomotor activity J:69590
impaired behavioral response to cocaine J:69590
increased B cell proliferation J:43975
increased dopamine level J:69590
increased IgA level J:43975
increased IgG3 level J:43975
increased IgM level J:43975
Cd81tm1Lvy/Cd81tm1Lvy
B6ByJ.129-Cd81tm1Lvy 		normal nervous system phenotype J:79426
Cd81tm1Lvy/Cd81tm1Lvy
CByJ.129-Cd81tm1Lvy 		abnormal T-helper 2 physiology J:46171
decreased susceptibility to type I hypersensitivity reaction J:46171
increased brain weight J:79426
increased hippocampus volume J:79426
thickened cerebral cortex J:79426
Cd81tm1Lvy/Cd81tm1Lvy
either: (B6ByJ.129-Cd81tm1Lvy x CByJ.129-Cd81tm1Lvy)F1 or (CByJ.129-Cd81tm1Lvy x B6ByJ.129-Cd81tm1Lvy)F1 		abnormal CNS glial cell morphology J:79426
abnormal corpus callosum morphology J:79426
abnormal hippocampus CA1 region morphology J:79426
abnormal hippocampus morphology J:79426
abnormal hippocampus pyramidal cell morphology J:79426
abnormal microglial cell morphology J:79426
abnormal neuron morphology J:79426
increased astrocyte number J:79426
increased brain weight J:79426
increased hippocampus volume J:79426
thickened cerebral cortex J:79426
Cd81tm1Lvy/Cd81tm1Lvy
involves: 129S1/Sv * 129X1/SvJ 		abnormal B cell morphology J:40394
abnormal T-helper 2 physiology J:40394
decreased IgG1 level J:40394
decreased IgG level J:40394
decreased susceptibility to parasitic infection J:126000
Cd81tm1Lvy/Cd81tm1Lvy
involves: 129S1/Sv * 129X1/SvJ * NIHS-BC 		abnormal CNS glial cell morphology J:79426
abnormal hippocampus CA1 region morphology J:79426
abnormal hippocampus morphology J:79426
abnormal hippocampus pyramidal cell morphology J:79426
abnormal neuron morphology J:79426
increased astrocyte number J:79426
increased brain weight J:79426
increased hippocampus volume J:79426
thickened cerebral cortex J:79426
Cd81tm1Tmiy/Cd81tm1Tmiy
involves: 129/Sv * C57BL/6 		abnormal B cell differentiation J:41830
abnormal immune system cell morphology J:41830
abnormal macrophage physiology J:83795
abnormal T cell proliferation J:41830
decreased B cell proliferation J:41830
decreased B-1 B cell number J:41830
increased B cell proliferation J:41830
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory