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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Cyp26a1
cytochrome P450, family 26, subfamily a, polypeptide 1
MGI:1096359
46 phenotypes from 3 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Cyp26a1tm1.1Hmd/Cyp26a1tm1.1Hmd
involves: 129S1/Sv * 129X1/SvJ * C57BL/6Cr
abnormal digestive system development J:67375
abnormal heart morphology J:67375
abnormal hindbrain development J:67375
abnormal hindlimb morphology J:67375
abnormal nervous system morphology J:119939
abnormal neural tube morphology J:67375
abnormal somite development J:67375
absent tail J:67375
exencephaly J:67375
fused kidneys J:67375
incomplete embryo turning J:67375
normal nervous system phenotype J:119939
open neural tube J:119939
perinatal lethality, complete penetrance J:67375
prenatal lethality, incomplete penetrance J:67375
sirenomelia J:67375
vertebral transformation J:67375
Cyp26a1tm1.1Ptk/Cyp26a1tm1.1Ptk
involves: 129S2/SvPas * C57BL/6 * SJL
abnormal digestive system development J:67399
abnormal heart development J:67399
abnormal heart looping J:67399
abnormal hindgut morphology J:67399
abnormal hindlimb morphology J:67399
abnormal kidney morphology J:67399
abnormal maxillary nerve morphology J:67399
abnormal mesonephros morphology J:67399
abnormal ophthalmic nerve morphology J:67399
abnormal primitive urogenital sinus morphology J:67399
abnormal reproductive system development J:67399
abnormal trigeminal ganglion morphology J:67399
abnormal trigeminal nerve morphology J:67399
abnormal urinary system development J:67399
abnormal vertebrae morphology J:67399
caudal body truncation J:67399
cervical vertebral transformation J:67399
curly tail J:67399
distended pericardium J:67399
exencephaly J:67399
genital tubercle hypoplasia J:67399
herniated abdominal wall J:67399
increased rhombomere 4 size J:67399
increased rib number J:67399
pelvic kidney J:67399
prenatal lethality, complete penetrance J:67399
rhombomere transformation J:67399
rib fusion J:67399
short tail J:67399
sirenomelia J:67399
spina bifida J:67399
Cyp26a1tm1Hmd/Cyp26a1tm1.1Hmd
involves: 129S1/Sv * 129X1/SvJ * C57BL/6Cr
kinked tail J:67375
short tail J:67375
Cyp26a1tm1Hmd/Cyp26a1tm1Hmd
involves: 129S1/SvJ * 129X1/SvJ * C57BL/6Cr
no abnormal phenotype detected J:67375

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/10/2019
MGI 6.14
The Jackson Laboratory