46 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Amhr2tm3(cre)Bhr/Amhr2+ Smad1tm2Rob/Smad1tm2.1Rob Smad5tm1Huy/Smad5tm1Huy involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6	early reproductive senescence	J:128934
	hemoperitoneum	J:128934
	increased ovarian carcinoma incidence	J:128934
	increased ovary tumor incidence	J:128934
	increased testis tumor incidence	J:128934
	male infertility	J:128934
Amhr2tm3(cre)Bhr/Amhr2+ Smad1tm2Rob/Smad1tm2.1Rob Smad5tm1Huy/Smad5tm1Huy involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6J	increased granulosa cell tumor incidence	J:157310
	premature death	J:157310
	suppressed circulating follicle stimulating hormone level	J:157310
Amhr2tm3(cre)Bhr/Amhr2+ Smad1tm2Rob/Smad1tm2Rob Smad5tm1Huy/Smad5tm1Huy involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6J	increased granulosa cell tumor incidence	J:157310
	premature death	J:157310
	suppressed circulating follicle stimulating hormone level	J:157310
Amhr2tm3(cre)Bhr/Amhr2+ Smad1tm2Rob/Smad1tm2Rob Smad5tm1Huy/Smad5tm1Zuk involves: 129P2/OlaHsd * 129S/SvEv * 129S7/SvEvBrd * C57BL/6	early reproductive senescence	J:128934
	hemoperitoneum	J:128934
	increased ovarian carcinoma incidence	J:128934
	increased ovary tumor incidence	J:128934
	increased testis tumor incidence	J:128934
	male infertility	J:128934
Amhr2tm3(cre)Bhr/Amhr2+ Smad1tm2Rob/Smad1tm2Rob Smad5tm1Huy/Smad5tm1Zuk involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6J	increased granulosa cell tumor incidence	J:157310
	premature death	J:157310
	suppressed circulating follicle stimulating hormone level	J:157310
Amhr2tm3(cre)Bhr/Amhr2+ Smad1tm2Rob/Smad1tm2Rob Smad5tm1Huy/Smad5tm1Zuk Smad9tm1Jfm/Smad9tm1Jfm involves: 129S/SvEv * 129S4/SvJaeSor * C57BL/6	early reproductive senescence	J:128934
	hemoperitoneum	J:128934
	increased ovarian carcinoma incidence	J:128934
	increased ovary tumor incidence	J:128934
Bmpr2tm1Mmue/Bmpr2+ Smad1tm1Rjle/Smad1+ involves: 129S1/SvImJ * 129S6/SvEvTac * C57BL/6	heart right ventricle hypertrophy	J:224752
	increased right ventricle systolic pressure	J:224752
Ltftm1(icre)Tdku/Ltf+ Smad1tm2Rob/Smad1tm2Rob Smad5tm1Huy/Smad5tm1Huy involves: 129P2/OlaHsd * 129S/SvEv * 129S6/SvEvTac * C57BL/6	abnormal decidualization	J:324161
	abnormal embryo attachment	J:324161
	abnormal embryo development	J:324161
	abnormal pregnancy	J:324161
	abnormal uterine receptivity	J:324161
	decreased litter size	J:324161
	delayed embryo implantation	J:324161
	early reproductive senescence	J:324161
	female infertility	J:324161
	impaired embryo implantation	J:324161
	reduced female fertility	J:324161
	normal reproductive system phenotype	J:324161
Smad1tm1Rob/Smad1+ Smad5tm1Zuk/Smad5+ involves: 129S/SvEv * 129S7/SvEvBrd	abnormal allantois morphology	J:119296
	abnormal direction of heart looping	J:119296
	abnormal forebrain morphology	J:119296
	abnormal heart development	J:119296
	abnormal heart looping	J:119296
	abnormal heart tube morphology	J:119296
	abnormal left-right axis patterning	J:119296
	abnormal mesoderm development	J:119296
	abnormal nervous system development	J:119296
	abnormal rostral-caudal axis patterning	J:119296
	abnormal somite development	J:119296
	absent primordial germ cells	J:119296
	absent second pharyngeal arch	J:119296
	absent third pharyngeal arch	J:119296
	decreased primordial germ cell number	J:119296
	embryonic lethality during organogenesis, complete penetrance	J:119296
	excessive folding of visceral yolk sac	J:119296
	failure of heart looping	J:119296
	incomplete rostral neuropore closure	J:119296
Smad1tm1Rob/Smad1+ Smad5tm1Zuk/Smad5+ Smad9tm2.1Rob/Smad9tm2.1Rob involves: 129S/SvEv * 129S7/SvEvBrd	prenatal lethality, complete penetrance	J:119296
Smad1tm1Rob/Smad1+ Smad9tm2.1Rob/Smad9tm2.1Rob involves: 129S/SvEv	abnormal embryo development	J:119296
	abnormal embryonic growth/weight/body size	J:119296
	abnormal embryonic tissue morphology	J:119296
	abnormal extraembryonic tissue morphology	J:119296
	abnormal heart development	J:119296
	abnormal nervous system development	J:119296
	embryonic lethality during organogenesis	J:119296