Fgf13 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Fgf13
fibroblast growth factor 13
MGI:109178

34 phenotypes from 3 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Fgf13^em1Xuzh/Y involves: C57BL/6J	abnormal axon extension	J:307501
	abnormal innervation	J:307501
	abnormal neuron differentiation	J:307501
	abnormal neuronal migration	J:307501
	abnormal spatial reference memory	J:307501
	abnormal stratification in cerebral cortex	J:307501
	decreased dendritic spine density	J:307501
	impaired contextual conditioning behavior	J:307501
	impaired cued conditioning behavior	J:307501
	impaired spatial learning	J:307501
	increased coping response	J:307501
Fgf13^tm1Jom/Y C57BL/6-Fgf13^tm1Jom	embryonic lethality during organogenesis, complete penetrance	J:222555
Fgf13^tm1Jom/Fgf13⁺ C57BL/6-Fgf13^tm1Jom	abnormal CNS synaptic transmission	J:222555
	abnormal inhibitory postsynaptic currents	J:222555
	abnormal kindling response	J:222555
	decreased miniature inhibitory postsynaptic current amplitude	J:222555
	environmentally induced seizures	J:222555
	increased excitatory postsynaptic current frequency	J:222555
	seizures	J:222555
Fgf13^tm1Xuzh/Y Emx1^tm1(cre)Yql/Emx1⁺ involves: 129S2/SvPas	abnormal axon morphology	J:186253
	abnormal cerebral cortex pyramidal cell morphology	J:186253
	abnormal depression-related behavior	J:186253
	abnormal object recognition memory	J:186253
	abnormal spatial learning	J:186253
	abnormal spatial working memory	J:186253
	behavioral despair	J:186253
	hyperactivity	J:186253
	impaired cued conditioning behavior	J:186253
	increased anxiety-related response	J:186253
Fgf13^tm1Xuzh/Fgf13^tm1Xuzh involves: 129	abnormal neuronal migration	J:186253
Fgf13^tm1Xuzh/Fgf13^tm1Xuzh Tg(EIIa-cre)C5379Lmgd/0 involves: 129 * FVB/N	abnormal neuron morphology	J:186253
	abnormal spatial learning	J:186253
	abnormal spatial working memory	J:186253
Fgf13^tm1Xuzh/Y Tg(EIIa-cre)C5379Lmgd/0 involves: 129 * FVB/N	abnormal cerebellar granule cell morphology	J:186253
	abnormal cerebral cortex pyramidal cell morphology	J:186253
	abnormal dentate gyrus morphology	J:186253
	abnormal hippocampus morphology	J:186253
	abnormal neuron morphology	J:186253
	abnormal spatial learning	J:186253
	abnormal spatial working memory	J:186253
	decreased neuron number	J:186253
	increased neuron number	J:186253

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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