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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Isl2
insulin related protein 2 (islet 2)
MGI:109156
9 phenotypes from 5 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Isl2tm1(Epha3)Grl/Isl2tm1(Epha3)Grl
involves: C57BL/6
no abnormal phenotype detected J:63516
Isl2tm1Gan/Isl2tm1Gan
Not Specified
no abnormal phenotype detected J:134978
Isl2tm2Slp/Isl2tm2Slp
involves: 129S1/Sv
abnormal innervation J:89755
abnormal motor neuron morphology J:89755
abnormal neuron specification J:89755
distended abdomen J:89755
neonatal lethality, complete penetrance J:89755
Isl2tm3.1(Mnx1-Lhx3)Slp/Isl2+
Not Specified
abnormal axon morphology J:63774, J:122940
abnormal motor neuron innervation pattern J:63774
abnormal motor neuron morphology J:63774
neonatal lethality, complete penetrance J:63774
respiratory failure J:63774
Isl2tm3.1(Mnx1-Lhx3)Slp/Isl2+
Tg(Mnx1-GFP)1Slp/?
Not Specified
abnormal motor neuron morphology J:122940
Mnx1tm4(cre)Tmj/Mnx1+
Isl2tm1Arbr/Isl2+
involves: 129S7/SvEvBrd * C57BL/6J
abnormal motor neuron morphology J:69623, J:76364

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/11/2020
MGI 6.14
The Jackson Laboratory