Tubb5 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Tubb5
tubulin, beta 5 class I
MGI:107812

17 phenotypes from 2 alleles in 1 genetic background

Allelic Composition Genetic Background	Annotated Term	Reference
Tubb5^tm1.1Dak/Tubb5⁺ Tg(Nes-cre)1Kln/0 involves: 129P2/OlaHsd * C57BL/6 * SJL	normal nervous system phenotype	J:240157
Tubb5^tm1.1Dak/Tubb5^tm1.1Dak Tg(Nes-cre)1Kln/0 involves: 129P2/OlaHsd * C57BL/6 * SJL	abnormal cerebellar layer morphology	J:240157
	abnormal mitosis	J:240157
	abnormal mitotic spindle morphology	J:240157
	abnormal neuron morphology	J:240157
	abnormal putamen morphology	J:240157
	decreased brain size	J:240157
	decreased corpus callosum size	J:240157
	increased neuron apoptosis	J:240157
	microcephaly	J:240157
	small cerebellum	J:240157
	small hippocampus	J:240157
	small olfactory bulb	J:240157
	small thalamus	J:240157
	thin cerebral cortex	J:240157
Tubb5^tm2.1Dak/Tubb5⁺ Tg(Nes-cre)1Kln/0 involves: 129P2/OlaHsd * C57BL/6 * SJL	abnormal cerebellar layer morphology	J:240157
	abnormal putamen morphology	J:240157
	decreased brain size	J:240157
	decreased corpus callosum size	J:240157
	increased neuron apoptosis	J:240157
	microcephaly	J:240157
	small cerebellum	J:240157
	small hippocampus	J:240157
	small olfactory bulb	J:240157
	small thalamus	J:240157
	thin cerebral cortex	J:240157
Tubb5^tm2.1Dak/Tubb5^tm2.1Dak Tg(Nes-cre)1Kln/0 involves: 129P2/OlaHsd * C57BL/6 * SJL	abnormal mitosis	J:240157
	normal nervous system phenotype	J:240157
	postnatal lethality, complete penetrance	J:240157
	prenatal lethality, incomplete penetrance	J:240157

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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