Akr1b8 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Akr1b8
aldo-keto reductase family 1, member B8
MGI:107673

11 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Akr1b8^{tm1.1(KOMP)Vlcg}/Akr1b8^{tm1.1(KOMP)Vlcg} B6N(Cg)-Akr1b8^{tm1.1(KOMP)Vlcg}/J	decreased fasting circulating glucose level	J:211773
	increased grip strength	J:211773
Akr1b8^tm1Dgen/Akr1b8^tm1Dgen Not Specified	abnormal interferon level	J:301852
	abnormal interleukin level	J:301852
	abnormal intestine physiology	J:301852
	abnormal large intestine crypts of Lieberkuhn morphology	J:301852
	decreased lipogenesis	J:301852
	impaired intestine regeneration	J:301852
	increased incidence of tumors by chemical induction	J:301852
	increased susceptibility to induced colitis	J:301852
	oxidative stress	J:301852

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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