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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Skil
SKI-like
MGI:106203
25 phenotypes from 4 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Skiltm1.1Kluo/Skiltm1.1Kluo
B6.129P2-Skiltm1.1Kluo
decreased fibroblast proliferation J:154718
decreased incidence of tumors by chemical induction J:154718
decreased tumor growth/size J:154718
early cellular replicative senescence J:154718
prenatal lethality, incomplete penetrance J:154718
Skiltm1Sis/Skil+
involves: C57BL/6 * CBA
cachexia J:62174
increased B cell derived lymphoma incidence J:62174
increased incidence of tumors by chemical induction J:62174
increased sensitivity to xenobiotic induced morbidity/mortality J:62174
increased T cell derived lymphoma incidence J:62174
Skiltm1Sis/Skiltm1Sis
involves: C57BL/6 * CBA
embryonic lethality before implantation, complete penetrance J:62174
failure of zygotic cell division J:62174
Skiltm1Spw/Skiltm1Spw
either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal immune system cell morphology J:84554
abnormal immune system organ morphology J:84554
decreased T cell proliferation J:84554
enlarged spleen J:84554
normal neoplasm J:84554
Skiltm2Spw/Skiltm2Spw
either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
decreased T cell proliferation J:84554
normal immune system phenotype J:84554
normal neoplasm J:84554
Skiltm2Spw/Skiltm2Spw
involves: 129S1/Sv * 129X1/SvJ
abnormal mammary gland alveolus morphology J:222343
abnormal mammary gland epithelium morphology J:222343
abnormal mammary gland growth during lactation J:222343
abnormal mammary gland luminal epithelium morphology J:222343
abnormal mammary gland physiology J:222343
hypolactation J:222343
impaired mammary gland growth during pregnancy J:222343

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
01/07/2020
MGI 6.14
The Jackson Laboratory