Mcm2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Mcm2
minichromosome maintenance complex component 2
MGI:105380

21 phenotypes from 3 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Mcm2^{Gt(AB0178)Wtsi}/Mcm2⁺ involves: 129P2/OlaHsd * C3HeB/FeJ	abnormal erythrocyte morphology	J:165667
	chromosomal instability	J:165667
Mcm2^{Gt(AB0178)Wtsi}/Mcm2^{Gt(AB0178)Wtsi} involves: 129P2/OlaHsd * C3HeB/FeJ	prenatal lethality, complete penetrance	J:165667
Mcm2^{tm1(cre/ERT2)Scpr}/Mcm2^{tm1(cre/ERT2)Scpr} involves: 129S6/SvEvTac	abnormal breathing pattern	J:141493
	abnormal cell cycle	J:141493
	abnormal cell nucleus morphology	J:141493
	abnormal coat/hair pigmentation	J:141493
	abnormal erythrocyte morphology	J:141493
	abnormal postnatal subventricular zone morphology	J:141493
	abnormal small intestinal villus morphology	J:141493
	abnormal small intestine crypts of Lieberkuhn morphology	J:141493
	colon polyps	J:141493
	decreased locomotor activity	J:141493
	decreased total body fat amount	J:141493
	enlarged spleen	J:141493
	hunched posture	J:141493
	increased thymoma incidence	J:141493
	intestine polyps	J:141493
	muscle weakness	J:141493
	premature death	J:141493
	sparse hair	J:141493
Mcm2^tm2Scpr/Mcm2^tm2Scpr involves: 129S6/SvEvTac	no abnormal phenotype detected	J:141950

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/16/2024 MGI 6.23