Mcm2^tm2Scpr
Targeted Allele Detail

Summary

• Symbol: Mcm2^tm2Scpr
• Name: minichromosome maintenance complex component 2; targeted mutation 2, Steven C Pruitt
• MGI ID: MGI:3820530
• Synonyms: Mcm2^IRES-EGFP
• Gene: Mcm2 Location: Chr6:88860456-88875762 bp, - strand Genetic Position: Chr6, 39.64 cM
• Alliance: Mcm2^tm2Scpr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:141950
• Parent Cell Line: W4 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Reporter)
• Mutation: Insertion
• Mutation details: An IRES-EGFP and PGK-neo cassette was inserted into the XbaI restriction site found in exon 16 after the stop codon. Gene expression is normal in Northern blots and by immunological tests. (J:141950)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Mcm2 Mutation: 49 strains or lines available

References

• Original: J:141950 Maslov AY, et al., Stem/progenitor cell-specific enhanced green fluorescent protein expression driven by the endogenous Mcm2 promoter. Stem Cells. 2007 Jan;25(1):132-8
• All: 1 reference(s)