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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Adcyap1
adenylate cyclase activating polypeptide 1
MGI:105094
47 phenotypes from 4 alleles in 7 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Adcyap1tm1Aba/Adcyap1tm1Aba
either: (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129P2/OlaHsd * C57BL/6 * ICR)
decreased anxiety-related response J:72576
decreased grooming behavior J:72576
hyperactivity J:72576
increased exploration in new environment J:72576
increased vertical activity J:72576
postnatal lethality, incomplete penetrance J:72576
reduced female fertility J:102717
reduced fertility J:72576
Adcyap1tm1Aba/Adcyap1tm1Aba
involves: 129P2/OlaHsd * C57BL/6
abnormal cornea morphology J:240066
abnormal corneal epithelium morphology J:240066
corneal opacity J:240066
decreased tear production J:240066
Adcyap1tm1Aba/Adcyap1tm1Aba
involves: 129P2/OlaHsd * C57BL/6 * ICR
abnormal mating frequency J:102717
absent maternal crouching J:102717
decreased litter size J:102717
reduced female fertility J:102717
Adcyap1tm1Clw/Adcyap1tm1Clw
B6.129S4-Adcyap1tm1Clw
abnormal regulatory T cell physiology J:194151
abnormal T cell activation J:194151
decreased dopaminergic neuron number J:194151
increased microglial cell activation J:194151
increased susceptibility to dopaminergic neuron neurotoxicity J:194151
increased T-helper 17 cell number J:194151
Adcyap1tm1Clw/Adcyap1tm1Clw
involves: 129S4/SvJae * C57BL/6
abnormal circadian behavior phase J:94880
increased locomotor activity J:94880
preweaning lethality, incomplete penetrance J:94880
shortened circadian behavior period J:94880
Adcyap1tm1Eid/Adcyap1tm1Eid
involves: 129S4/SvJae * C57BL/6
decreased adrenaline level J:73702
decreased circulating adrenaline level J:73702
hypoglycemia J:73702
normal nervous system phenotype J:73702
Adcyap1tm1Nms/Adcyap1tm1Nms
B6.129-Adcyap1tm1Nms
abnormal sexual interaction J:131950
decreased circulating progesterone level J:131950
decreased circulating prolactin level J:131950
impaired embryo implantation J:131950
postnatal lethality, incomplete penetrance J:131950
reduced female fertility J:131950
slow postnatal weight gain J:131950
Adcyap1tm1Nms/Adcyap1tm1Nms
either: (involves: 129S1/Sv * 129X1/SvJ * C57BL/6) or (involves: C57BL/6)
abnormal skeletal muscle morphology J:71968
decreased liver glycogen level J:71968
decreased white adipose tissue amount J:71968
hypoglycemia J:71968
impaired adaptive thermogenesis J:79468
increased circulating cholesterol level J:71968
increased circulating corticosterone level J:71968
increased circulating free fatty acids level J:71968
increased circulating insulin level J:71968
increased circulating ketone body level J:71968
increased circulating triglyceride level J:71968
microvesicular hepatic steatosis J:71968
postnatal lethality, complete penetrance J:71968, J:79468
weight loss J:71968

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory