Adcyap1tm1Eid
Targeted Allele Detail
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Symbol: |
Adcyap1tm1Eid |
Name: |
adenylate cyclase activating polypeptide 1; targeted mutation 1, Lee E Eiden |
MGI ID: |
MGI:2159730 |
Synonyms: |
PACAP- |
Gene: |
Adcyap1 Location: Chr17:93506448-93513967 bp, + strand Genetic Position: Chr17, 60.67 cM
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Alliance: |
Adcyap1tm1Eid page
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Germline Transmission: |
Earliest citation of germline transmission:
J:73702
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Parent Cell Line: |
J1 (ES Cell)
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Strain of Origin: |
129S4/SvJae
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Allele Type: |
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Targeted (Null/knockout) |
Mutations: |
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Insertion, Intragenic deletion
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Mutation details: A PGK-neomycin resistance cassette replaced the ORF. Immunohistochemical studies of hypothalamus and IML of spinal cord did not detect protein in homozygous mice. Quantitative RT-PCR studies of hypothalamus and spinal cord did not detect mRNA in homozygous mutant mice.
(J:73702)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Adcyap1 Mutation: |
22 strains or lines available
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Original: |
J:73702 Hamelink C, et al., Pituitary adenylate cyclase-activating polypeptide is a sympathoadrenal neurotransmitter involved in catecholamine regulation and glucohomeostasis. Proc Natl Acad Sci U S A. 2002 Jan 8;99(1):461-6 |
All: |
11 reference(s) |
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