Pls3 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Pls3
plastin 3 (T-isoform)
MGI:104807

33 phenotypes from 4 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Pls3^em1Bult/Y C57BL/6J-Pls3^em1Bult/BultJ	abnormal abdominal muscle morphology	J:341714
	abnormal abdominal wall morphology	J:341714
	abnormal diaphragm morphology	J:341714
	diaphragmatic hernia	J:341714
	herniated abdominal wall	J:341714
	homeostasis/metabolism phenotype	J:341714
	increased bone mineral density	J:341714
	neonatal lethality, incomplete penetrance	J:341714
	postnatal lethality, incomplete penetrance	J:341714
	preweaning lethality	J:341714
	respiratory system phenotype	J:341714
	thin diaphragm muscle	J:341714
Pls3^em1Bult/Pls3^em1Bult C57BL/6J-Pls3^em1Bult/BultJ	abnormal abdominal muscle morphology	J:341714
	abnormal abdominal wall morphology	J:341714
	abnormal body wall morphology	J:341714
	abnormal diaphragm development	J:341714
	abnormal diaphragm morphology	J:341714
	diaphragmatic hernia	J:341714
	herniated abdominal wall	J:341714
	normal homeostasis/metabolism phenotype	J:341714
	increased bone mineral density	J:341714
	neonatal lethality, incomplete penetrance	J:341714
	postnatal lethality, incomplete penetrance	J:341714
	preweaning lethality	J:341714
	normal respiratory system phenotype	J:341714
	thin diaphragm muscle	J:341714
Pls3^em2Bult/Y C57BL/6J-Pls3^em2Bult/BultJ	decreased bone mineral density	J:341714
Pls3^em2Bult/Pls3^em2Bult C57BL/6J-Pls3^em2Bult/BultJ	decreased bone mineral density	J:341714
Pls3^{tm1a(EUCOMM)Wtsi}/Y C57BL/6N-Pls3^{tm1a(EUCOMM)Wtsi}/Wtsi	increased circulating phosphate level	J:211773
	increased circulating triglyceride level	J:211773
	increased grip strength	J:211773
Pls3^{tm1a(EUCOMM)Wtsi}/Pls3^{tm1a(EUCOMM)Wtsi} C57BL/6N-Pls3^{tm1a(EUCOMM)Wtsi}/Wtsi	increased circulating alkaline phosphatase level	J:211773
	increased mean corpuscular hemoglobin	J:211773
Pls3^{tm1d(EUCOMM)Wtsi}/Y involves: BALB/cJ * C57BL/6N * C57BL/6NTac * SJL	abnormal skeleton physiology	J:267292
	decreased bone stiffness	J:267292
	decreased bone strength	J:267292
	decreased bone trabecula number	J:267292
	decreased compact bone area	J:267292
	decreased femur compact bone thickness	J:267292
	increased bone resorption	J:267292
	increased bone trabecular spacing	J:267292
	osteoporosis	J:267292
	normal skeleton phenotype	J:267292
Pls3^{tm1d(EUCOMM)Wtsi}/Pls3^{tm1d(EUCOMM)Wtsi} involves: BALB/cJ * C57BL/6N * C57BL/6NTac * SJL	abnormal skeleton physiology	J:267292
	decreased bone trabecula number	J:267292
	decreased bone volume	J:267292
	decreased compact bone area	J:267292
	decreased femur compact bone thickness	J:267292
	increased bone resorption	J:267292
	increased bone trabecular spacing	J:267292
	osteoporosis	J:267292
	normal skeleton phenotype	J:267292

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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