About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Col4a3
collagen, type IV, alpha 3
MGI:104688
22 phenotypes from multigenic genotypes
Export: Excel File
Allelic Composition
Genetic Background
Annotated Term Reference
Col4a3tm1Dec/Col4a3tm1Dec
Itga1tm1Gdnr/Itga1tm1Gdnr
involves: 129S4/SvJae * 129X1/SvJ * BALB/c
abnormal kidney morphology J:71378
abnormal renal glomerulus basement membrane morphology J:91620
increased circulating total protein level J:91620
kidney failure J:91620
tubular nephritis J:71378
Col4a3tm1Dec/Col4a3tm1Dec
Sostdc1tm1Myan/Sostdc1tm1Myan
involves: 129X1/SvJ
albuminuria J:158731
decreased systemic arterial systolic blood pressure J:158731
extended life span J:158731
glomerulonephritis J:158731
glomerulosclerosis J:158731
increased blood urea nitrogen level J:158731
increased circulating creatinine level J:158731
renal cast J:158731
renal interstitial fibrosis J:158731
renal tubule atrophy J:158731
Col4a3tm1Jhm/Col4a3tm1Jhm
Gt(ROSA)26Sortm1(rtTA,EGFP)Nagy/Gt(ROSA)26Sor+
Tg(tetO-COL4A3/Col4a3)#aJhm/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA
increased renal glomerulus basement membrane thickness J:207595
normal renal/urinary system phenotype J:207595
Col4a3tm1Jhm/Col4a3tm1Jhm
Lamb2em1Jhm/Lamb2+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * CBA/J
abnormal kidney morphology J:280129
abnormal renal glomerulus basement membrane morphology J:280129
albuminuria J:280129
glomerular crescent J:280129
glomerulosclerosis J:280129
increased blood urea nitrogen level J:280129
kidney failure J:280129
podocyte foot process effacement J:280129
premature death J:280129
Col4a3tm1Jhm/Col4a3tm1Jhm
Lamb2em1Jhm/Lamb2em1Jhm
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * CBA/J
abnormal renal glomerulus basement membrane morphology J:280129
glomerulosclerosis J:280129
podocyte foot process effacement J:280129
Col4a3tm1Jhm/Col4a3tm1Jhm
Mmp9tm1Tvu/Mmp9tm1Tvu
involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ
abnormal renal glomerulus basement membrane morphology J:63137
glomerulonephritis J:63137
increased renal glomerulus basement membrane thickness J:63137
Col4a3tm1Jhm/Col4a3tm1Jhm
Tg(Nphs1-rtTA*3G)8Jhm/0
Tg(tetO-COL4A3/Col4a3)#aJhm/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA
abnormal podocyte foot process morphology J:207595
abnormal renal glomerulus basement membrane morphology J:207595
increased renal glomerulus basement membrane thickness J:207595
normal mortality/aging J:207595
normal renal/urinary system phenotype J:207595

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
03/31/2020
MGI 6.15
The Jackson Laboratory