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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Aqp1
aquaporin 1
MGI:103201
34 phenotypes from 2 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Aqp1tm1Ask/Aqp1tm1Ask
involves: C57BL/6J
abnormal renal water transport J:45888, J:102454
decreased body weight J:45888
decreased urine osmolality J:45888
decreased urine sodium level J:45888
dehydration J:45888
normal endocrine/exocrine gland phenotype J:56302
increased blood osmolality J:45888
lethargy J:45888
postnatal growth retardation J:45888
prenatal lethality, incomplete penetrance J:56302
Aqp1tm1Ask/Aqp1tm1Ask
involves: C57BL/6J * CD-1
abnormal myocardial fiber physiology J:116293
abnormal respiratory system physiology J:106259
normal behavior/neurological phenotype J:123606
decreased vascular permeability J:106259
dilated rete testis J:125658
normal hearing/vestibular/ear phenotype J:71154
normal nervous system phenotype J:123606
postnatal growth retardation J:106259
normal vision/eye phenotype J:62579, J:126927
Aqp1tm1b(EUCOMM)Wtsi/Aqp1tm1b(EUCOMM)Wtsi
C57BL/6N-Aqp1tm1b(EUCOMM)Wtsi/H
decreased bone mineral content J:211773
decreased bone mineral density J:211773
decreased circulating chloride level J:211773
decreased exploration in new environment J:211773
decreased grip strength J:211773
decreased locomotor activity J:211773
decreased total body fat amount J:211773
impaired glucose tolerance J:211773
increased circulating alkaline phosphatase level J:211773
increased circulating amylase level J:211773
increased circulating cholesterol level J:211773
increased circulating creatinine level J:211773
increased circulating HDL cholesterol level J:211773
increased circulating total protein level J:211773
increased lean body mass J:211773
increased neutrophil cell number J:211773

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory