36 phenotypes from 4 alleles in 10 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Mcm4chaos3/Mcm4+ involves: C57BL/6J	abnormal cell nucleus morphology	J:117494
Mcm4chaos3/Mcm4chaos3 C3.B6-Mcm4chaos3	increased hepatocellular carcinoma incidence	J:117494
	increased lung adenocarcinoma incidence	J:117494
	increased mammary adenocarcinoma incidence	J:117494
	increased mammary gland tumor incidence	J:117494
Mcm4chaos3/Mcm4chaos3 involves: C3HeB/FeJ * C57BL/6J	abnormal cell cycle	J:117494
	decreased cell proliferation	J:117494
Mcm4chaos3/Mcm4chaos3 involves: C57BL/6J	abnormal cell nucleus morphology	J:117494
	abnormal erythrocyte morphology	J:117494, J:165667
	chromosomal instability	J:165667
	increased lymphoma incidence	J:165667
	increased mammary gland tumor incidence	J:165667
	increased T cell derived lymphoma incidence	J:165667
	premature death	J:165667
Mcm4chaos3/Mcm4Gt(RRE056)Byg B6.Cg-Mcm4chaos3 Mcm4Gt(RRE056)Byg	abnormal cell cycle	J:117494
	decreased fibroblast proliferation	J:117494
	embryonic growth retardation	J:117494
	induced chromosome breakage	J:117494
	lethality throughout fetal growth and development, complete penetrance	J:117494
Mcm4chaos3/Mcm4Gt(RRE056)Byg involves: 129P2/OlaHsd * C3HeB/FeJ * C57BL/6J	abnormal digestive system development	J:117494
	fetal growth retardation	J:117494
	perinatal lethality, incomplete penetrance	J:117494, J:165667
	postnatal lethality, incomplete penetrance	J:165667
Mcm4chaos3/Mcm4Sdla involves: C57BL/6 * C57BL/6J	prenatal lethality, complete penetrance	J:194117
Mcm4Gt(RRE056)Byg/Mcm4+ involves: 129P2/OlaHsd	no abnormal phenotype detected	J:117494
Mcm4Gt(RRE056)Byg/Mcm4+ involves: 129P2/OlaHsd * C3HeB/FeJ	abnormal erythrocyte morphology	J:165667
	chromosomal instability	J:165667
Mcm4Gt(RRE056)Byg/Mcm4Gt(RRE056)Byg involves: 129P2/OlaHsd	absent inner cell mass proliferation	J:117494
	embryonic lethality between implantation and somite formation, complete penetrance	J:117494
Mcm4Sdla/Mcm4+ involves: C57BL/6	decreased DN1 thymic pro-T cell number	J:194117
	enlarged lymph nodes	J:194117
	enlarged spleen	J:194117
	increased acute lymphoblastic leukemia incidence	J:194117
	increased tumor incidence	J:194117
	induced chromosome breakage	J:194117
	reticulocytosis	J:194117
	spontaneous chromosome breakage	J:194117
Mcm4Sdla/Mcm4Sdla involves: C57BL/6	embryonic lethality, complete penetrance	J:194117
Mcm4tm1b(KOMP)Mbp/Mcm4+ C57BL/6N-Mcm4tm1b(KOMP)Mbp/J	increased grip strength	J:211773
Mcm4tm1b(KOMP)Mbp/Mcm4tm1b(KOMP)Mbp C57BL/6N-Mcm4tm1b(KOMP)Mbp/J	embryonic lethality prior to organogenesis	J:211773
	embryonic lethality prior to tooth bud stage	J:211773
	preweaning lethality, complete penetrance	J:211773