Uimc1 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Uimc1
ubiquitin interaction motif containing 1
MGI:103185

15 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Uimc1^{Gt(RRN158)Byg}/Uimc1^{Gt(RRN158)Byg} involves: 129P2/OlaHsd * C57BL/6	abnormal DNA repair	J:188388
	chromosome breakage	J:188388
	decreased tumor-free survival time	J:188388
	increased B cell derived lymphoma incidence	J:188388
	increased cellular sensitivity to gamma-irradiation	J:188388
	increased mortality induced by gamma-irradiation	J:188388
	increased tumor incidence	J:188388
Uimc1^tm1.2Amj/Uimc1^tm1.2Amj involves: BALB/cJ * C57BL/6	abnormal cell cycle checkpoint function	J:191827
	decreased fibroblast proliferation	J:191827
	early cellular replicative senescence	J:191827
	increased B cell derived lymphoma incidence	J:191827
	increased incidence of tumors by chemical induction	J:191827
	increased incidence of tumors by ionizing radiation induction	J:191827
	increased lymphoma incidence	J:191827
	increased susceptibility to xenobiotic induced morbidity/mortality	J:191827
	increased T cell derived lymphoma incidence	J:191827

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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