Slc9a1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Slc9a1
solute carrier family 9 (sodium/hydrogen exchanger), member 1
MGI:102462

42 phenotypes from 3 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Slc9a1^em1(IMPC)Mbp/Slc9a1⁺ C57BL/6N-Slc9a1^em1(IMPC)Mbp/MbpMmucd	polycystic kidney	J:211773
Slc9a1^em1(IMPC)Mbp/Slc9a1^em1(IMPC)Mbp C57BL/6N-Slc9a1^em1(IMPC)Mbp/MbpMmucd	male infertility	J:211773
Slc9a1^swe/Slc9a1^swe (SJL/J-Slc9a1^swe x B6.SJL-Slc9a1^swe)F1	premature death	J:43429
	preweaning lethality, incomplete penetrance	J:43429
Slc9a1^swe/Slc9a1^swe B6.SJL-Slc9a1^swe	abnormal axon morphology	J:199873
	abnormal cerebellar molecular layer	J:43429
	abnormal cerebellum deep nucleus morphology	J:43429
	abnormal cerebellum dentate nucleus morphology	J:43429
	abnormal Purkinje cell axon morphology	J:199873
	abnormal synaptic bouton morphology	J:199873
	abnormal vestibular ganglion morphology	J:43429
	ataxia	J:43429
	axon degeneration	J:199873
	cochlear ganglion degeneration	J:43429
	decreased body size	J:43429
	neuron degeneration	J:43429
	postnatal lethality, incomplete penetrance	J:43429
	premature death	J:43429
	Purkinje cell degeneration	J:199873
	seizures	J:43429
	tonic-clonic seizures	J:43429
Slc9a1^swe/Slc9a1^swe involves: C57BL/6J * SJL/J	absence seizures	J:43429
	behavioral arrest	J:43429
	premature death	J:43429
	seizures	J:43429
	tonic-clonic seizures	J:43429
Slc9a1^swe/Slc9a1^swe SJL/J-Slc9a1^swe/J	abnormal gait	J:43429
	abnormal locomotor coordination	J:43429
	ataxia	J:43429
	decreased body size	J:43429
	normal growth/size/body region phenotype	J:43429
	postnatal lethality	J:43429
	premature death	J:43429
	seizures	J:43429
	tonic-clonic seizures	J:43429
Slc9a1^tm1Smb/Slc9a1^tm1Smb involves: 129X1/SvJ * Black Swiss	abnormal epidermis stratum corneum morphology	J:54705
	abnormal fertility/fecundity	J:54705
	abnormal parotid gland physiology	J:70551
	abnormal stomach glandular epithelium morphology	J:54705
	ataxia	J:54705
	convulsive seizures	J:54705
	decreased body weight	J:54705
	decreased exploration in new environment	J:54705
	decreased heart weight	J:109389
	decreased response of heart to induced stress	J:109389
	decreased salivation	J:70551
	normal endocrine/exocrine gland phenotype	J:68659
	normal homeostasis/metabolism phenotype	J:54705
	lethality at weaning, incomplete penetrance	J:54705
	normal nervous system phenotype	J:54705
	poor grooming	J:54705
	thin skin	J:54705

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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