Plk4 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Plk4
polo like kinase 4
MGI:101783

13 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Plk4^Gt(XK603)Byg/Plk4⁺ involves: 129P2/OlaHsd	normal reproductive system phenotype	J:177071
Plk4^Gt(XK603)Byg/Plk4⁺ involves: 129P2/OlaHsd	small testis	J:177071
Plk4^Gt(XK603)Byg/Plk4^Gt(XK603)Byg involves: 129P2/OlaHsd	embryonic lethality, complete penetrance	J:177071
Plk4^Gt(XK603)Byg/Plk4^m1Lja involves: 129P2/OlaHsd * C57BL/6J	embryonic lethality, complete penetrance	J:177071
Plk4^m1Lja/Plk4⁺ C57BL/6J-Plk4^m1Lja	decreased male germ cell number	J:177071
	decreased testis weight	J:177071
	increased circulating follicle stimulating hormone level	J:177071
	normal reproductive system phenotype	J:177071
	small testis	J:177071
Plk4^m1Lja/Plk4^m1Lja C57BL/6J-Plk4^m1Lja	embryonic lethality, complete penetrance	J:177071
Plk4^tm1Jwd/Plk4^tm1Jwd either: 129 or (involves: 129S1/Sv * 129X1/SvJ * CD-1)	abnormal apoptosis	J:68142
	abnormal mitosis	J:68142
	abnormal neural tube morphology	J:68142
	absent somites	J:68142
	decreased embryo size	J:68142
	embryonic growth arrest	J:68142
	embryonic lethality between implantation and somite formation, complete penetrance	J:68142

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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