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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Cdk5r1
cyclin dependent kinase 5, regulatory subunit 1
MGI:101764
24 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background
Annotated Term Reference
Cdk5r1tm1Lht/Cdk5r1+
Cdk5r2tm1Lht/Cdk5r2tm1Lht
involves: 129S4/SvJae * C57BL/6
abnormal cerebellum morphology J:71181
abnormal cortical marginal zone morphology J:71181
abnormal hippocampus layer morphology J:71181
abnormal neuron differentiation J:71181
small cerebellum J:71181
thin cortical plate J:71181
Cdk5r1tm1Lht/Cdk5r1tm1Lht
Cdk5r2tm1Lht/Cdk5r2+
involves: 129S4/SvJae * C57BL/6
abnormal cerebellum morphology J:71181
abnormal hippocampus layer morphology J:71181
normal nervous system phenotype J:71181
premature death J:71181
small cerebellum J:71181
Cdk5r1tm1Lht/Cdk5r1tm1Lht
Cdk5r2tm1Lht/Cdk5r2tm1Lht
involves: 129S4/SvJae * C57BL/6
abnormal cerebellum development J:71181
abnormal cerebellum external granule cell layer morphology J:71181
abnormal cerebral cortex morphology J:71181
abnormal cortical marginal zone morphology J:71181
abnormal cortical plate morphology J:71181
abnormal dentate gyrus morphology J:71181
abnormal hippocampus layer morphology J:71181
abnormal motor neuron morphology J:71181
abnormal neuron differentiation J:71181
abnormal olfactory bulb development J:71181
absent cerebellar foliation J:71181
absent Purkinje cell layer J:71181
chromatolysis J:71181
decreased embryo size J:71181
perinatal lethality, incomplete penetrance J:71181
small cerebellum J:71181
thin cortical plate J:71181
unresponsive to tactile stimuli J:71181
weakness J:71181
Cdk5r1tm2.1Lht/?
Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas/?
involves: 129S4/SvJaeSor * C57BL/6 * SJL
amyloid beta deposits J:208030
normal behavior/neurological phenotype J:208030
normal nervous system phenotype J:208030

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory