GO Annotations Graph

• Symbol: Adcy1
• Name: adenylate cyclase 1
• ID: MGI:99677

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0004016	adenylate cyclase activity	IBA	J:265628
Molecular Function	GO:0004016	adenylate cyclase activity	IGI	J:57343
Molecular Function	GO:0004016	adenylate cyclase activity	TAS	J:48517
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0008294	calcium- and calmodulin-responsive adenylate cyclase activity	ISO	J:155856
Molecular Function	GO:0005516	calmodulin binding	IEA	J:60000
Molecular Function	GO:0016829	lyase activity	IEA	J:60000
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0016849	phosphorus-oxygen lyase activity	IEA	J:72247
Cellular Component	GO:0005737	cytoplasm	IDA	J:213883
Cellular Component	GO:0098978	glutamatergic synapse	IMP	J:47002
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:47002
Cellular Component	GO:0098978	glutamatergic synapse	IMP	J:57343
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:57343
Cellular Component	GO:0098686	hippocampal mossy fiber to CA3 synapse	IDA	J:47002
Cellular Component	GO:0098686	hippocampal mossy fiber to CA3 synapse	IMP	J:47002
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	TAS	J:48517
Cellular Component	GO:0014069	postsynaptic density	IDA	J:134966
Cellular Component	GO:0098839	postsynaptic density membrane	IDA	J:122007
Cellular Component	GO:0098839	postsynaptic density membrane	IEP	J:122007
Cellular Component	GO:0098839	postsynaptic density membrane	IDA	J:122007
Cellular Component	GO:0098839	postsynaptic density membrane	IDA	J:122007
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	IMP	J:57343
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	IDA	J:57343
Biological Process	GO:0007190	activation of adenylate cyclase activity	TAS	J:48517
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	IBA	J:265628
Biological Process	GO:0007409	axonogenesis	IMP	J:118610
Biological Process	GO:0007409	axonogenesis	IMP	J:118610
Biological Process	GO:0006171	cAMP biosynthetic process	ISO	J:155856
Biological Process	GO:0006171	cAMP biosynthetic process	IBA	J:265628
Biological Process	GO:0009190	cyclic nucleotide biosynthetic process	IEA	J:72247
Biological Process	GO:0035556	intracellular signal transduction	IEA	J:72247
Biological Process	GO:0007616	long-term memory	IGI	J:57343
Biological Process	GO:0050804	modulation of chemical synaptic transmission	IMP	J:57343
Biological Process	GO:0050804	modulation of chemical synaptic transmission	IDA	J:57343
Biological Process	GO:0050804	modulation of chemical synaptic transmission	IDA	J:57343
Biological Process	GO:0050804	modulation of chemical synaptic transmission	IMP	J:57343
Biological Process	GO:0150076	neuroinflammatory response	IMP	J:107678
Biological Process	GO:0032793	positive regulation of CREB transcription factor activity	IMP	J:107678
Biological Process	GO:1900273	positive regulation of long-term synaptic potentiation	IMP	J:57343
Biological Process	GO:0099171	presynaptic modulation of chemical synaptic transmission	IDA	J:47002
Biological Process	GO:0099171	presynaptic modulation of chemical synaptic transmission	IMP	J:47002
Biological Process	GO:0099171	presynaptic modulation of chemical synaptic transmission	IDA	J:47002
Biological Process	GO:0099171	presynaptic modulation of chemical synaptic transmission	IMP	J:47002
Biological Process	GO:0042752	regulation of circadian rhythm	IMP	J:202325
Biological Process	GO:0048511	rhythmic process	IEA	J:60000