GO Annotations Graph

• Symbol: Cckbr
• Name: cholecystokinin B receptor
• ID: MGI:99479

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0004951	cholecystokinin receptor activity	ISO	J:164563
Molecular Function	GO:0004951	cholecystokinin receptor activity	IBA	J:265628
Molecular Function	GO:0004930	G protein-coupled receptor activity	IEA	J:72247
Molecular Function	GO:0004930	G protein-coupled receptor activity	IEA	J:60000
Molecular Function	GO:0015054	gastrin receptor activity	ISO	J:164563
Molecular Function	GO:0015054	gastrin receptor activity	ISO	J:155856
Molecular Function	GO:0015054	gastrin receptor activity	IBA	J:265628
Molecular Function	GO:0017046	peptide hormone binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:35876
Molecular Function	GO:0005515	protein binding	IPI	J:35876
Molecular Function	GO:0005515	protein binding	IPI	J:35876
Molecular Function	GO:0005515	protein binding	IPI	J:35876
Molecular Function	GO:0031741	type B gastrin/cholecystokinin receptor binding	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:164563
Cellular Component	GO:0016020	membrane	IDA	J:35876
Cellular Component	GO:0016020	membrane	IDA	J:35876
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Biological Process	GO:0006915	apoptotic process	ISO	J:155856
Biological Process	GO:0002209	behavioral defense response	ISO	J:155856
Biological Process	GO:0038188	cholecystokinin signaling pathway	ISO	J:164563
Biological Process	GO:0048565	digestive tract development	IMP	J:102139
Biological Process	GO:0070371	ERK1 and ERK2 cascade	ISO	J:155856
Biological Process	GO:0044849	estrous cycle	ISO	J:155856
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	IEA	J:72247
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	IEA	J:60000
Biological Process	GO:0001696	gastric acid secretion	IGI	J:102139
Biological Process	GO:0001696	gastric acid secretion	IMP	J:102139
Biological Process	GO:0048732	gland development	IMP	J:102139
Biological Process	GO:0001821	histamine secretion	ISO	J:155856
Biological Process	GO:0045851	pH reduction	IMP	J:151255
Biological Process	GO:0007200	phospholipase C-activating G protein-coupled receptor signaling pathway	ISO	J:164563
Biological Process	GO:0007200	phospholipase C-activating G protein-coupled receptor signaling pathway	IBA	J:265628
Biological Process	GO:2000987	positive regulation of behavioral fear response	ISO	J:155856
Biological Process	GO:0008284	positive regulation of cell population proliferation	ISO	J:164563
Biological Process	GO:0008284	positive regulation of cell population proliferation	ISO	J:155856
Biological Process	GO:0007204	positive regulation of cytosolic calcium ion concentration	ISO	J:164563
Biological Process	GO:0090274	positive regulation of somatostatin secretion	ISO	J:155856
Biological Process	GO:0050806	positive regulation of synaptic transmission	ISO	J:155856
Biological Process	GO:0032230	positive regulation of synaptic transmission, GABAergic	ISO	J:155856
Biological Process	GO:0051968	positive regulation of synaptic transmission, glutamatergic	ISO	J:155856
Biological Process	GO:0051930	regulation of sensory perception of pain	ISO	J:155856
Biological Process	GO:0007165	signal transduction	IEA	J:60000