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GO Annotations Graph
Symbol
Name
ID
Fasl
Fas ligand (TNF superfamily, member 6)
MGI:99255

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.
CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:0005125cytokine activityIEAJ:60000
Molecular FunctionGO:0005123death receptor bindingISOJ:155856
Molecular FunctionGO:0005164tumor necrosis factor receptor bindingISOJ:155856
Cellular ComponentGO:0005901caveolaISOJ:155856
Cellular ComponentGO:0009986cell surfaceIDAJ:224737
Cellular ComponentGO:0031410cytoplasmic vesicleIEAJ:60000
Cellular ComponentGO:0016023cytoplasmic, membrane-bounded vesicleISOJ:155856
Cellular ComponentGO:0009897external side of plasma membraneIDAJ:113553
Cellular ComponentGO:0070062extracellular exosomeISOJ:164563
Cellular ComponentGO:0005576extracellular regionIEAJ:60000
Cellular ComponentGO:0005615extracellular spaceISOJ:164563
Cellular ComponentGO:0016021integral component of membraneIEAJ:60000
Cellular ComponentGO:0005764lysosomeIEAJ:60000
Cellular ComponentGO:0016020membraneIEAJ:60000
Cellular ComponentGO:0016020membraneIEAJ:72247
Cellular ComponentGO:0045121membrane raftISOJ:155856
Cellular ComponentGO:0005634nucleusISOJ:164563
Cellular ComponentGO:0048471perinuclear region of cytoplasmISOJ:155856
Cellular ComponentGO:0005886plasma membraneISOJ:164563
Biological ProcessGO:0006919activation of cysteine-type endopeptidase activity involved in apoptotic processISOJ:73065
Biological ProcessGO:0006915apoptotic processIEAJ:72247
Biological ProcessGO:0006915apoptotic processIEAJ:60000
Biological ProcessGO:0097190apoptotic signaling pathwayIDAJ:17445
Biological ProcessGO:0097190apoptotic signaling pathwayISOJ:164563
Biological ProcessGO:0097190apoptotic signaling pathwayIDAJ:95351
Biological ProcessGO:0030644cellular chloride ion homeostasisISOJ:155856
Biological ProcessGO:0048388endosomal lumen acidificationISOJ:155856
Biological ProcessGO:0097191extrinsic apoptotic signaling pathwayISOJ:164563
Biological ProcessGO:0008625extrinsic apoptotic signaling pathway via death domain receptorsISOJ:155856
Biological ProcessGO:0008625extrinsic apoptotic signaling pathway via death domain receptorsISOJ:164563
Biological ProcessGO:0008625extrinsic apoptotic signaling pathway via death domain receptorsIDAJ:113782
Biological ProcessGO:0008625extrinsic apoptotic signaling pathway via death domain receptorsIDAJ:89131
Biological ProcessGO:0006955immune responseIEAJ:72247
Biological ProcessGO:0006925inflammatory cell apoptotic processISOJ:155856
Biological ProcessGO:0070266necroptotic processISOJ:164563
Biological ProcessGO:0097527necroptotic signaling pathwayISOJ:164563
Biological ProcessGO:0016525negative regulation of angiogenesisISOJ:164563
Biological ProcessGO:0000122negative regulation of transcription from RNA polymerase II promoterISOJ:164563
Biological ProcessGO:0043065positive regulation of apoptotic processISOJ:87682
Biological ProcessGO:0043065positive regulation of apoptotic processISOJ:164563
Biological ProcessGO:0043065positive regulation of apoptotic processISOJ:73065
Biological ProcessGO:0008284positive regulation of cell proliferationISOJ:155856
Biological ProcessGO:2000353positive regulation of endothelial cell apoptotic processISOJ:164563
Biological ProcessGO:0045742positive regulation of epidermal growth factor receptor signaling pathwayISOJ:155856
Biological ProcessGO:0043525positive regulation of neuron apoptotic processISOJ:155856
Biological ProcessGO:0006355regulation of transcription, DNA-templatedIEAJ:60000
Biological ProcessGO:0046666retinal cell programmed cell deathIMPJ:85918
Biological ProcessGO:0070231T cell apoptotic processISOJ:164563
Biological ProcessGO:0006351transcription, DNA-templatedIEAJ:60000


Gene Ontology Evidence Code Abbreviations:

Experimental:
EXP
Inferred from experiment
HMP
Inferred from high throughput mutant phenotype
HGI
Inferred from high throughput genetic interaction
HDA
Inferred from high throughput direct assay
HEP
Inferred from high throughput expression pattern
IDA
Inferred from direct assay
IEP
Inferred from expression pattern
IGI
Inferred from genetic interaction
IMP
Inferred from mutant phenotype
IPI
Inferred from physical interaction
Homology:
IAS
Inferred from ancestral sequence
IBA
Inferred from biological aspect of ancestor
IBD
Inferred from biological aspect of descendant
IKR
Inferred from key residues
IMR
Inferred from missing residues
IRD
Inferred from rapid divergence
ISA
Inferred from sequence alignment
ISM
Inferred from sequence model
ISO
Inferred from sequence orthology
ISS
Inferred from sequence or structural similarity
Automated:
IEA
Inferred from electronic annotation
RCA
Reviewed computational analysis
Other:
IC
Inferred by curator
NAS
Non-traceable author statement
ND
No biological data available
TAS
Traceable author statement


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
01/12/2021
MGI 6.16
The Jackson Laboratory