Wnt3a GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Wnt3a
wingless-type MMTV integration site family, member 3A
MGI:98956

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0039706	co-receptor binding	ISO	J:164563
Molecular Function	GO:0005125	cytokine activity	IBA	J:265628
Molecular Function	GO:0005109	frizzled binding	IBA	J:265628
Molecular Function	GO:0005109	frizzled binding	IDA	J:156508
Molecular Function	GO:0005109	frizzled binding	IPI	J:140886
Molecular Function	GO:0042802	identical protein binding	IPI	J:326900
Molecular Function	GO:0005515	protein binding	IPI	J:187646
Molecular Function	GO:0005515	protein binding	IPI	J:245356
Molecular Function	GO:0005515	protein binding	IPI	J:201290
Molecular Function	GO:0005515	protein binding	IPI	J:255336
Molecular Function	GO:0005515	protein binding	IPI	J:245252
Molecular Function	GO:0005515	protein binding	IPI	J:166025
Molecular Function	GO:0005515	protein binding	IPI	J:137648
Molecular Function	GO:0005515	protein binding	IPI	J:326900
Molecular Function	GO:0005515	protein binding	IPI	J:227371
Molecular Function	GO:0005515	protein binding	IPI	J:216033
Molecular Function	GO:0005515	protein binding	IPI	J:184507
Molecular Function	GO:0005515	protein binding	IPI	J:164374
Molecular Function	GO:0005515	protein binding	IPI	J:93897
Molecular Function	GO:0005515	protein binding	IPI	J:140886
Molecular Function	GO:0005515	protein binding	IPI	J:140886
Molecular Function	GO:0005515	protein binding	IPI	J:63226
Molecular Function	GO:0005515	protein binding	IPI	J:121773
Molecular Function	GO:0005515	protein binding	IPI	J:299450
Molecular Function	GO:0005515	protein binding	IPI	J:121773
Molecular Function	GO:0019904	protein domain specific binding	IPI	J:93897
Molecular Function	GO:0048018	receptor ligand activity	ISO	J:164563
Molecular Function	GO:0048018	receptor ligand activity	IDA	J:161039
Molecular Function	GO:0005102	signaling receptor binding	ISO	J:164563
Molecular Function	GO:0005102	signaling receptor binding	TAS	J:52010
Molecular Function	GO:0003713	transcription coactivator activity	IDA	J:164778
Cellular Component	GO:0009986	cell surface	IDA	J:21428
Cellular Component	GO:0005788	endoplasmic reticulum lumen	TAS	Reactome:R-MMU-3238687
Cellular Component	GO:0005788	endoplasmic reticulum lumen	TAS	Reactome:R-MMU-3238692
Cellular Component	GO:0005576	extracellular region	IEA	J:72247
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0005576	extracellular region	TAS	Reactome:R-MMU-3769366
Cellular Component	GO:0005576	extracellular region	TAS	Reactome:R-NUL-3772439
Cellular Component	GO:0005615	extracellular space	IDA	J:255336
Cellular Component	GO:0005615	extracellular space	IDA	J:166025
Cellular Component	GO:0005615	extracellular space	ISO	J:164563
Cellular Component	GO:0005615	extracellular space	IBA	J:265628
Cellular Component	GO:0005615	extracellular space	IDA	J:93897
Cellular Component	GO:0098978	glutamatergic synapse	ISO	J:164563
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:263445
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:263445
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:263445
Cellular Component	GO:0098978	glutamatergic synapse	EXP	J:263445
Cellular Component	GO:0098978	glutamatergic synapse	IMP	J:263445
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:263445
Cellular Component	GO:0098978	glutamatergic synapse	EXP	J:263445
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:263445
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:263445
Cellular Component	GO:0045202	synapse	IDA	J:263445
Cellular Component	GO:0045202	synapse	IDA	J:263445
Cellular Component	GO:1990909	Wnt signalosome	IC	J:161039
Cellular Component	GO:1990909	Wnt signalosome	NAS	J:188340
Cellular Component	GO:1990851	Wnt-Frizzled-LRP5/6 complex	ISO	J:164563
Biological Process	GO:0009887	animal organ morphogenesis	TAS	J:52010
Biological Process	GO:0009952	anterior/posterior pattern specification	IDA	J:90666
Biological Process	GO:0090245	axis elongation involved in somitogenesis	IGI	J:64989
Biological Process	GO:0007411	axon guidance	IDA	J:138829
Biological Process	GO:0007409	axonogenesis	IGI	J:93897
Biological Process	GO:0007409	axonogenesis	IDA	J:93897
Biological Process	GO:0042100	B cell proliferation	IDA	J:63678
Biological Process	GO:0030509	BMP signaling pathway	ISO	J:157031
Biological Process	GO:0090676	calcium ion transmembrane transport via low voltage-gated calcium channel	IDA	J:165064
Biological Process	GO:0060070	canonical Wnt signaling pathway	IDA	J:165064
Biological Process	GO:0060070	canonical Wnt signaling pathway	IDA	J:227371
Biological Process	GO:0060070	canonical Wnt signaling pathway	IDA	J:161039
Biological Process	GO:0060070	canonical Wnt signaling pathway	IDA	J:172892
Biological Process	GO:0060070	canonical Wnt signaling pathway	IDA	J:228115
Biological Process	GO:0060070	canonical Wnt signaling pathway	IDA	J:164774
Biological Process	GO:0060070	canonical Wnt signaling pathway	IDA	J:227384
Biological Process	GO:0060070	canonical Wnt signaling pathway	ISO	J:164563
Biological Process	GO:0060070	canonical Wnt signaling pathway	IDA	J:164788
Biological Process	GO:0060070	canonical Wnt signaling pathway	IMP	J:255336
Biological Process	GO:0060070	canonical Wnt signaling pathway	IDA	J:120773
Biological Process	GO:0060070	canonical Wnt signaling pathway	IBA	J:265628
Biological Process	GO:0060070	canonical Wnt signaling pathway	IDA	J:175318
Biological Process	GO:0060070	canonical Wnt signaling pathway	IDA	J:127355
Biological Process	GO:0060070	canonical Wnt signaling pathway	IDA	J:121773
Biological Process	GO:0060070	canonical Wnt signaling pathway	IDA	J:113117
Biological Process	GO:0060070	canonical Wnt signaling pathway	IDA	J:138624
Biological Process	GO:0060070	canonical Wnt signaling pathway	IDA	J:294316
Biological Process	GO:0060070	canonical Wnt signaling pathway	IGI	J:63678
Biological Process	GO:0060070	canonical Wnt signaling pathway	IGI	J:106895
Biological Process	GO:0060070	canonical Wnt signaling pathway	IGI	J:154476
Biological Process	GO:0060070	canonical Wnt signaling pathway	IDA	J:154024
Biological Process	GO:0060070	canonical Wnt signaling pathway	IGI	J:106895
Biological Process	GO:0060070	canonical Wnt signaling pathway	IDA	J:107727
Biological Process	GO:0060070	canonical Wnt signaling pathway	IDA	J:204847
Biological Process	GO:0060070	canonical Wnt signaling pathway	IDA	J:97443
Biological Process	GO:0060070	canonical Wnt signaling pathway	IDA	J:96879
Biological Process	GO:0060070	canonical Wnt signaling pathway	IDA	J:140886
Biological Process	GO:0060070	canonical Wnt signaling pathway	IGI	J:156508
Biological Process	GO:0060070	canonical Wnt signaling pathway	IGI	J:91019
Biological Process	GO:0060070	canonical Wnt signaling pathway	IGI	J:156721
Biological Process	GO:0060070	canonical Wnt signaling pathway	IDA	J:145745
Biological Process	GO:0060070	canonical Wnt signaling pathway	IGI	J:56401
Biological Process	GO:0060070	canonical Wnt signaling pathway	IGI	J:64989
Biological Process	GO:0060070	canonical Wnt signaling pathway	IMP	J:152701
Biological Process	GO:0060070	canonical Wnt signaling pathway	IGI	J:56401
Biological Process	GO:0060070	canonical Wnt signaling pathway	IGI	J:156508
Biological Process	GO:0060070	canonical Wnt signaling pathway	IDA	J:149821
Biological Process	GO:0060070	canonical Wnt signaling pathway	IGI	J:155567
Biological Process	GO:0060070	canonical Wnt signaling pathway	IDA	J:156721
Biological Process	GO:0060070	canonical Wnt signaling pathway	IGI	J:154476
Biological Process	GO:0061317	canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment	ISO	J:164563
Biological Process	GO:0060923	cardiac muscle cell fate commitment	IGI	J:177756
Biological Process	GO:0045165	cell fate commitment	IBA	J:265628
Biological Process	GO:0008283	cell population proliferation	ISO	J:164563
Biological Process	GO:0021846	cell proliferation in forebrain	IDA	J:84335
Biological Process	GO:0033278	cell proliferation in midbrain	IDA	J:86401
Biological Process	GO:0007267	cell-cell signaling	TAS	J:52010
Biological Process	GO:0010387	COP9 signalosome assembly	IDA	J:166016
Biological Process	GO:0001816	cytokine production	IDA	J:204847
Biological Process	GO:0007368	determination of left/right symmetry	IMP	J:104377
Biological Process	GO:0071542	dopaminergic neuron differentiation	TAS	J:227390
Biological Process	GO:0021904	dorsal/ventral neural tube patterning	IMP	J:16716
Biological Process	GO:0030198	extracellular matrix organization	IDA	J:135507
Biological Process	GO:0045444	fat cell differentiation	IGI	J:127355
Biological Process	GO:0045444	fat cell differentiation	IGI	J:127355
Biological Process	GO:0045444	fat cell differentiation	IDA	J:127355
Biological Process	GO:0001947	heart looping	IMP	J:104377
Biological Process	GO:0030097	hemopoiesis	IDA	J:83550
Biological Process	GO:0021766	hippocampus development	IMP	J:59283
Biological Process	GO:0001701	in utero embryonic development	IMP	J:5431
Biological Process	GO:0042472	inner ear morphogenesis	IGI	J:99408
Biological Process	GO:0030879	mammary gland development	IDA	J:98338
Biological Process	GO:0007498	mesoderm development	IMP	J:16716
Biological Process	GO:0030901	midbrain development	IDA	J:86401
Biological Process	GO:0050804	modulation of chemical synaptic transmission	IDA	J:263445
Biological Process	GO:0050804	modulation of chemical synaptic transmission	IMP	J:263445
Biological Process	GO:0050804	modulation of chemical synaptic transmission	IDA	J:263445
Biological Process	GO:0050804	modulation of chemical synaptic transmission	EXP	J:263445
Biological Process	GO:0050804	modulation of chemical synaptic transmission	IDA	J:263445
Biological Process	GO:0007275	multicellular organism development	IEA	J:72247
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0045445	myoblast differentiation	IGI	J:154476
Biological Process	GO:0045445	myoblast differentiation	IGI	J:154476
Biological Process	GO:0048843	negative regulation of axon extension involved in axon guidance	IDA	J:138829
Biological Process	GO:1904339	negative regulation of dopaminergic neuron differentiation	IDA	J:86401
Biological Process	GO:0045599	negative regulation of fat cell differentiation	IGI	J:127355
Biological Process	GO:0045599	negative regulation of fat cell differentiation	IDA	J:97443
Biological Process	GO:0045599	negative regulation of fat cell differentiation	IDA	J:127355
Biological Process	GO:0045599	negative regulation of fat cell differentiation	IGI	J:127355
Biological Process	GO:0003136	negative regulation of heart induction by canonical Wnt signaling pathway	ISO	J:164563
Biological Process	GO:0050768	negative regulation of neurogenesis	IDA	J:84335
Biological Process	GO:1901215	negative regulation of neuron death	IGI	J:239211
Biological Process	GO:0010977	negative regulation of neuron projection development	IDA	J:175303
Biological Process	GO:0022008	neurogenesis	IDA	J:86401
Biological Process	GO:0030182	neuron differentiation	IBA	J:265628
Biological Process	GO:0001649	osteoblast differentiation	IGI	J:107256
Biological Process	GO:0048343	paraxial mesodermal cell fate commitment	IMP	J:39344
Biological Process	GO:0030168	platelet activation	IDA	J:154748
Biological Process	GO:0070527	platelet aggregation	IDA	J:154748
Biological Process	GO:0030890	positive regulation of B cell proliferation	IDA	J:63678
Biological Process	GO:0090263	positive regulation of canonical Wnt signaling pathway	ISO	J:164563
Biological Process	GO:0090263	positive regulation of canonical Wnt signaling pathway	IDA	J:201786
Biological Process	GO:0090263	positive regulation of canonical Wnt signaling pathway	IDA	J:130875
Biological Process	GO:2000081	positive regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation	IDA	J:164778
Biological Process	GO:2000727	positive regulation of cardiac muscle cell differentiation	ISO	J:164563
Biological Process	GO:0008284	positive regulation of cell population proliferation	IDA	J:164778
Biological Process	GO:0008284	positive regulation of cell population proliferation	IDA	J:152705
Biological Process	GO:2000049	positive regulation of cell-cell adhesion mediated by cadherin	IDA	J:161589
Biological Process	GO:0048697	positive regulation of collateral sprouting in absence of injury	IDA	J:138829
Biological Process	GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	IDA	J:119489
Biological Process	GO:0001819	positive regulation of cytokine production	IDA	J:204847
Biological Process	GO:0061184	positive regulation of dermatome development	ISO	J:164563
Biological Process	GO:0051091	positive regulation of DNA-binding transcription factor activity	IDA	J:164774
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:164778
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:164774
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:44227
Biological Process	GO:0010628	positive regulation of gene expression	ISO	J:164563
Biological Process	GO:2000347	positive regulation of hepatocyte proliferation	IDA	J:201786
Biological Process	GO:0048337	positive regulation of mesodermal cell fate specification	ISO	J:164563
Biological Process	GO:2000179	positive regulation of neural precursor cell proliferation	IDA	J:154024
Biological Process	GO:0033138	positive regulation of peptidyl-serine phosphorylation	ISO	J:164563
Biological Process	GO:0032092	positive regulation of protein binding	ISO	J:164563
Biological Process	GO:0045860	positive regulation of protein kinase activity	IDA	J:120773
Biological Process	GO:1903078	positive regulation of protein localization to plasma membrane	IDA	J:188340
Biological Process	GO:0001934	positive regulation of protein phosphorylation	ISO	J:164563
Biological Process	GO:0001934	positive regulation of protein phosphorylation	IDA	J:228115
Biological Process	GO:0001934	positive regulation of protein phosphorylation	IDA	J:120773
Biological Process	GO:0061098	positive regulation of protein tyrosine kinase activity	IGI	J:155567
Biological Process	GO:0002092	positive regulation of receptor internalization	ISO	J:164563
Biological Process	GO:0048643	positive regulation of skeletal muscle tissue development	IMP	J:76366
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	NAS	J:185349
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:165064
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:154476
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:201786
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:154476
Biological Process	GO:0036342	post-anal tail morphogenesis	IMP	J:16716
Biological Process	GO:0008104	protein localization	IDA	J:124214
Biological Process	GO:0050770	regulation of axonogenesis	IGI	J:138829
Biological Process	GO:0045595	regulation of cell differentiation	IDA	J:83550
Biological Process	GO:0070507	regulation of microtubule cytoskeleton organization	IGI	J:138829
Biological Process	GO:1905539	regulation of postsynapse to nucleus signaling pathway	IDA	J:263445
Biological Process	GO:1905539	regulation of postsynapse to nucleus signaling pathway	EXP	J:263445
Biological Process	GO:1905606	regulation of presynapse assembly	ISO	J:164563
Biological Process	GO:2001141	regulation of RNA biosynthetic process	IDA	J:186636
Biological Process	GO:0050807	regulation of synapse organization	ISO	J:164563
Biological Process	GO:0062009	secondary palate development	ISO	J:164563
Biological Process	GO:0007165	signal transduction	TAS	J:52010
Biological Process	GO:0035914	skeletal muscle cell differentiation	IGI	J:154476
Biological Process	GO:0035914	skeletal muscle cell differentiation	IGI	J:154476
Biological Process	GO:0048103	somatic stem cell division	IDA	J:83550
Biological Process	GO:0001756	somitogenesis	IMP	J:88851
Biological Process	GO:0001756	somitogenesis	IMP	J:104377
Biological Process	GO:0001756	somitogenesis	IMP	J:16716
Biological Process	GO:0021527	spinal cord association neuron differentiation	IDA	J:75367
Biological Process	GO:0021527	spinal cord association neuron differentiation	IGI	J:75367
Biological Process	GO:0006366	transcription by RNA polymerase II	IGI	J:154476
Biological Process	GO:0006366	transcription by RNA polymerase II	IGI	J:154476
Biological Process	GO:0016055	Wnt signaling pathway	IGI	J:106895
Biological Process	GO:0016055	Wnt signaling pathway	IGI	J:106895
Biological Process	GO:0016055	Wnt signaling pathway	IGI	J:106895
Biological Process	GO:0021874	Wnt signaling pathway involved in forebrain neuroblast division	IMP	J:59283

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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