GO Annotations Graph

• Symbol: Il1rl1
• Name: interleukin 1 receptor-like 1
• ID: MGI:98427

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0004908	interleukin-1 receptor activity	IEA	J:72247
Molecular Function	GO:0002113	interleukin-33 binding	IPI	J:274274
Molecular Function	GO:0002113	interleukin-33 binding	IBA	J:265628
Molecular Function	GO:0050135	NAD(P)+ nucleosidase activity	IEA	J:72245
Molecular Function	GO:0061809	NAD+ nucleotidase, cyclic ADP-ribose generating	IEA	J:72245
Molecular Function	GO:0005515	protein binding	IPI	J:151287
Molecular Function	GO:0005515	protein binding	IPI	J:127627
Molecular Function	GO:0005515	protein binding	IPI	J:187651
Cellular Component	GO:0009986	cell surface	ISO	J:155856
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0009897	external side of plasma membrane	ISO	J:73065
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:151963
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:84889
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0005615	extracellular space	ISO	J:155856
Cellular Component	GO:0005925	focal adhesion	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Biological Process	GO:0006954	inflammatory response	IMP	J:319416
Biological Process	GO:0030225	macrophage differentiation	IMP	J:319416
Biological Process	GO:0008285	negative regulation of cell population proliferation	ISO	J:155856
Biological Process	GO:0002826	negative regulation of T-helper 1 type immune response	IGI	J:132106
Biological Process	GO:0032689	negative regulation of type II interferon production	IGI	J:132106
Biological Process	GO:0032722	positive regulation of chemokine production	IMP	J:157197
Biological Process	GO:0050729	positive regulation of inflammatory response	IMP	J:157197
Biological Process	GO:0032754	positive regulation of interleukin-5 production	IGI	J:132106
Biological Process	GO:0043032	positive regulation of macrophage activation	IMP	J:157197
Biological Process	GO:0007165	signal transduction	IEA	J:72247