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GO Annotations Graph
Symbol
Name
ID
Enpp1
ectonucleotide pyrophosphatase/phosphodiesterase 1
MGI:97370

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.
CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:0005524ATP bindingISOJ:164563
Molecular FunctionGO:0005509calcium ion bindingIDAJ:190295
Molecular FunctionGO:0003824catalytic activityIEAJ:72247
Molecular FunctionGO:0016787hydrolase activityIEAJ:72247
Molecular FunctionGO:0016787hydrolase activityIEAJ:60000
Molecular FunctionGO:0005158insulin receptor bindingISOJ:164563
Molecular FunctionGO:0046872metal ion bindingIEAJ:60000
Molecular FunctionGO:0046872metal ion bindingIEAJ:72247
Molecular FunctionGO:0035529NADH pyrophosphatase activityIEAJ:72245
Molecular FunctionGO:0003676nucleic acid bindingIEAJ:72247
Molecular FunctionGO:0047429nucleoside-triphosphate diphosphatase activityISOJ:164563
Molecular FunctionGO:0004551nucleotide diphosphatase activityISOJ:164563
Molecular FunctionGO:0004551nucleotide diphosphatase activityIDAJ:190295
Molecular FunctionGO:0004528phosphodiesterase I activityIDAJ:19267
Molecular FunctionGO:0030247polysaccharide bindingIEAJ:72247
Molecular FunctionGO:0042803protein homodimerization activityISOJ:164563
Molecular FunctionGO:0005044scavenger receptor activityIEAJ:72247
Molecular FunctionGO:0008270zinc ion bindingIDAJ:190295
Cellular ComponentGO:0009986cell surfaceIDAJ:133038
Cellular ComponentGO:0009986cell surfaceISOJ:164563
Cellular ComponentGO:0005576extracellular regionIEAJ:60000
Cellular ComponentGO:0005615extracellular spaceIDAJ:133038
Cellular ComponentGO:0005615extracellular spaceISOJ:164563
Cellular ComponentGO:0016021integral component of membraneIDAJ:19267
Cellular ComponentGO:0005887integral component of plasma membraneIDAJ:21444
Cellular ComponentGO:0005765lysosomal membraneISOJ:164563
Cellular ComponentGO:0016020membraneIEAJ:60000
Cellular ComponentGO:0005886plasma membraneISOJ:164563
Cellular ComponentGO:0005886plasma membraneISOJ:149519
Biological ProcessGO:00504273'-phosphoadenosine 5'-phosphosulfate metabolic processISOJ:164563
Biological ProcessGO:0031214biomineral tissue developmentIEAJ:60000
Biological ProcessGO:0046849bone remodelingIMPJ:53773
Biological ProcessGO:0030643cellular phosphate ion homeostasisISOJ:164563
Biological ProcessGO:0032869cellular response to insulin stimulusISOJ:164563
Biological ProcessGO:0006091generation of precursor metabolites and energyISOJ:164563
Biological ProcessGO:0006955immune responseIEAJ:72247
Biological ProcessGO:0030505inorganic diphosphate transportISOJ:164563
Biological ProcessGO:0008152metabolic processIEAJ:72247
Biological ProcessGO:0030308negative regulation of cell growthISOJ:164563
Biological ProcessGO:0045599negative regulation of fat cell differentiationIMPJ:133011
Biological ProcessGO:0045599negative regulation of fat cell differentiationISOJ:164563
Biological ProcessGO:0046325negative regulation of glucose importISOJ:164563
Biological ProcessGO:0045719negative regulation of glycogen biosynthetic processISOJ:164563
Biological ProcessGO:0046627negative regulation of insulin receptor signaling pathwayISOJ:164563
Biological ProcessGO:0030279negative regulation of ossificationIMPJ:48527
Biological ProcessGO:0031953negative regulation of protein autophosphorylationISOJ:164563
Biological ProcessGO:0009143nucleoside triphosphate catabolic processISOJ:164563
Biological ProcessGO:0006796phosphate-containing compound metabolic processISOJ:164563
Biological ProcessGO:0030730sequestering of triglycerideISOJ:164563


Gene Ontology Evidence Code Abbreviations:

Experimental:
EXP
Inferred from experiment
HMP
Inferred from high throughput mutant phenotype
HGI
Inferred from high throughput genetic interaction
HDA
Inferred from high throughput direct assay
HEP
Inferred from high throughput expression pattern
IDA
Inferred from direct assay
IEP
Inferred from expression pattern
IGI
Inferred from genetic interaction
IMP
Inferred from mutant phenotype
IPI
Inferred from physical interaction
Homology:
IAS
Inferred from ancestral sequence
IBA
Inferred from biological aspect of ancestor
IBD
Inferred from biological aspect of descendant
IKR
Inferred from key residues
IMR
Inferred from missing residues
IRD
Inferred from rapid divergence
ISA
Inferred from sequence alignment
ISM
Inferred from sequence model
ISO
Inferred from sequence orthology
ISS
Inferred from sequence or structural similarity
Automated:
IEA
Inferred from electronic annotation
RCA
Reviewed computational analysis
Other:
IC
Inferred by curator
NAS
Non-traceable author statement
ND
No biological data available
TAS
Traceable author statement


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/10/2020
MGI 6.16
The Jackson Laboratory