Myb GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Myb
myeloblastosis oncogene
MGI:97249

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003677	DNA binding	IDA	J:84061
Molecular Function	GO:0003677	DNA binding	IDA	J:177274
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	J:210934
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	ISO	J:164563
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IMP	J:84257
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:84061
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA	J:265628
Molecular Function	GO:0005515	protein binding	IPI	J:89440
Molecular Function	GO:0005515	protein binding	IPI	J:249964
Molecular Function	GO:0005515	protein binding	IPI	J:31923
Molecular Function	GO:0005515	protein binding	IPI	J:140200
Molecular Function	GO:0005515	protein binding	IPI	J:107109
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:210934
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0071987	WD40-repeat domain binding	IDA	J:107109
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005829	cytosol	IDA	J:107109
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-9616215
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-NUL-992753
Cellular Component	GO:0005634	nucleus	NAS	J:319971
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005634	nucleus	IDA	J:84061
Cellular Component	GO:0005634	nucleus	IDA	J:107109
Cellular Component	GO:0005634	nucleus	IDA	J:31923
Cellular Component	GO:0005634	nucleus	IDA	J:111418
Cellular Component	GO:0090575	RNA polymerase II transcription regulator complex	ISO	J:164563
Cellular Component	GO:0090575	RNA polymerase II transcription regulator complex	EXP	J:74346
Biological Process	GO:0030183	B cell differentiation	IMP	J:127324
Biological Process	GO:0006816	calcium ion transport	IMP	J:84257
Biological Process	GO:0071354	cellular response to interleukin-6	IDA	J:107109
Biological Process	GO:1990830	cellular response to leukemia inhibitory factor	IEP	J:163558
Biological Process	GO:0048566	embryonic digestive tract development	IMP	J:58207
Biological Process	GO:0030218	erythrocyte differentiation	ISO	J:164563
Biological Process	GO:0000082	G1/S transition of mitotic cell cycle	IMP	J:84257
Biological Process	GO:0048872	homeostasis of number of cells	IMP	J:127324
Biological Process	GO:0001701	in utero embryonic development	IMP	J:127324
Biological Process	GO:0001701	in utero embryonic development	IMP	J:58207
Biological Process	GO:0000278	mitotic cell cycle	IBA	J:265628
Biological Process	GO:0061515	myeloid cell development	NAS	J:320120
Biological Process	GO:0030099	myeloid cell differentiation	IMP	J:148788
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:1901533	negative regulation of hematopoietic progenitor cell differentiation	ISO	J:164563
Biological Process	GO:0045653	negative regulation of megakaryocyte differentiation	ISO	J:164563
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0032967	positive regulation of collagen biosynthetic process	ISO	J:155856
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0060252	positive regulation of glial cell proliferation	ISO	J:155856
Biological Process	GO:2000491	positive regulation of hepatic stellate cell activation	ISO	J:155856
Biological Process	GO:1904899	positive regulation of hepatic stellate cell proliferation	ISO	J:155856
Biological Process	GO:1902895	positive regulation of miRNA transcription	ISO	J:164563
Biological Process	GO:0043525	positive regulation of neuron apoptotic process	ISO	J:155856
Biological Process	GO:1901216	positive regulation of neuron death	ISO	J:155856
Biological Process	GO:0048661	positive regulation of smooth muscle cell proliferation	ISO	J:155856
Biological Process	GO:2000845	positive regulation of testosterone secretion	ISO	J:155856
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:210934
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	EXP	J:74346
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:89274
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:89274
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:89274
Biological Process	GO:0071636	positive regulation of transforming growth factor beta production	ISO	J:155856
Biological Process	GO:0006355	regulation of DNA-templated transcription	IDA	J:84061
Biological Process	GO:0006355	regulation of DNA-templated transcription	IMP	J:84257
Biological Process	GO:0010468	regulation of gene expression	IMP	J:58207
Biological Process	GO:0010468	regulation of gene expression	IMP	J:148788
Biological Process	GO:0048536	spleen development	IMP	J:148788
Biological Process	GO:0017145	stem cell division	IMP	J:148788
Biological Process	GO:0045064	T-helper 2 cell differentiation	ISO	J:164563
Biological Process	GO:0048538	thymus development	IMP	J:127324

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/16/2024 MGI 6.23