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GO Annotations Graph
Symbol
Name
ID
Lrp1
low density lipoprotein receptor-related protein 1
MGI:96828

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.
CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:0034185apolipoprotein bindingISOJ:164563
Molecular FunctionGO:0005509calcium ion bindingIDAJ:30078
Molecular FunctionGO:0046872metal ion bindingIEAJ:60000
Molecular FunctionGO:0044822poly(A) RNA bindingISOJ:164563
Molecular FunctionGO:0002020protease bindingISOJ:155856
Molecular FunctionGO:0005515protein bindingIPIJ:180555
Molecular FunctionGO:0005515protein bindingIPIJ:152628
Molecular FunctionGO:0005515protein bindingIPIJ:126954
Molecular FunctionGO:0005515protein bindingIPIJ:113901
Molecular FunctionGO:0005515protein bindingIPIJ:126870
Molecular FunctionGO:0005515protein bindingIPIJ:149003
Molecular FunctionGO:0032403protein complex bindingISOJ:164563
Cellular ComponentGO:0030136clathrin-coated vesicleISOJ:155856
Cellular ComponentGO:0005905coated pitIEAJ:60000
Cellular ComponentGO:0005737cytoplasmISOJ:164563
Cellular ComponentGO:0030425dendriteISOJ:155856
Cellular ComponentGO:0005768endosomeISOJ:155856
Cellular ComponentGO:0005925focal adhesionISOJ:164563
Cellular ComponentGO:0016021integral component of membraneIEAJ:60000
Cellular ComponentGO:0005887integral component of plasma membraneIDAJ:30078
Cellular ComponentGO:0005765lysosomal membraneISOJ:164563
Cellular ComponentGO:0016020membraneIDAJ:90197
Cellular ComponentGO:0043025neuronal cell bodyISOJ:155856
Cellular ComponentGO:0005730nucleolusISOJ:164563
Cellular ComponentGO:0005634nucleusIEAJ:60000
Cellular ComponentGO:0048471perinuclear region of cytoplasmISOJ:149003
Cellular ComponentGO:0005886plasma membraneIEAJ:60000
Cellular ComponentGO:0043235receptor complexISOJ:194542
Biological ProcessGO:0035909aorta morphogenesisIMPJ:153626
Biological ProcessGO:0043277apoptotic cell clearanceIMPJ:106377
Biological ProcessGO:0097242beta-amyloid clearanceIMPJ:187572
Biological ProcessGO:0003279cardiac septum developmentIMPJ:222159
Biological ProcessGO:0008283cell proliferationISOJ:155856
Biological ProcessGO:0008203cholesterol metabolic processIMPJ:126954
Biological ProcessGO:0060976coronary vasculature developmentIMPJ:222159
Biological ProcessGO:0006897endocytosisIEAJ:60000
Biological ProcessGO:0007275multicellular organism developmentIEAJ:60000
Biological ProcessGO:0043524negative regulation of neuron apoptotic processISOJ:155856
Biological ProcessGO:0010977negative regulation of neuron projection developmentISOJ:155856
Biological ProcessGO:2000587negative regulation of platelet-derived growth factor receptor-beta signaling pathwayIMPJ:153626
Biological ProcessGO:0014912negative regulation of smooth muscle cell migrationIMPJ:153626
Biological ProcessGO:0030178negative regulation of Wnt signaling pathwayIDAJ:106811
Biological ProcessGO:0010875positive regulation of cholesterol effluxIMPJ:152391
Biological ProcessGO:0032370positive regulation of lipid transportIMPJ:152391
Biological ProcessGO:0051222positive regulation of protein transportISOJ:155856
Biological ProcessGO:0007205protein kinase C-activating G-protein coupled receptor signaling pathwayISOJ:155856
Biological ProcessGO:0006898receptor-mediated endocytosisIDAJ:174507
Biological ProcessGO:0032956regulation of actin cytoskeleton organizationIMPJ:153626
Biological ProcessGO:0032374regulation of cholesterol transportIMPJ:152391
Biological ProcessGO:0032429regulation of phospholipase A2 activityIMPJ:152391


Gene Ontology Evidence Code Abbreviations:

Experimental:
EXP
Inferred from experiment
HMP
Inferred from high throughput mutant phenotype
HGI
Inferred from high throughput genetic interaction
HDA
Inferred from high throughput direct assay
HEP
Inferred from high throughput expression pattern
IDA
Inferred from direct assay
IEP
Inferred from expression pattern
IGI
Inferred from genetic interaction
IMP
Inferred from mutant phenotype
IPI
Inferred from physical interaction
Homology:
IAS
Inferred from ancestral sequence
IBA
Inferred from biological aspect of ancestor
IBD
Inferred from biological aspect of descendant
IKR
Inferred from key residues
IMR
Inferred from missing residues
IRD
Inferred from rapid divergence
ISA
Inferred from sequence alignment
ISM
Inferred from sequence model
ISO
Inferred from sequence orthology
ISS
Inferred from sequence or structural similarity
Automated:
IEA
Inferred from electronic annotation
RCA
Reviewed computational analysis
Other:
IC
Inferred by curator
NAS
Non-traceable author statement
ND
No biological data available
TAS
Traceable author statement


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/23/2021
MGI 6.17
The Jackson Laboratory