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GO Annotations Graph
Symbol
Name
ID
Itpr3
inositol 1,4,5-triphosphate receptor 3
MGI:96624

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.
CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:0005262calcium channel activityIEAJ:72247
Molecular FunctionGO:0005262calcium channel activityIEAJ:60000
Molecular FunctionGO:0005509calcium ion bindingISOJ:155856
Molecular FunctionGO:0043533inositol 1,3,4,5 tetrakisphosphate bindingISOJ:155856
Molecular FunctionGO:0070679inositol 1,4,5 trisphosphate bindingISOJ:164563
Molecular FunctionGO:0070679inositol 1,4,5 trisphosphate bindingISOJ:155856
Molecular FunctionGO:0005220inositol 1,4,5-trisphosphate-sensitive calcium-release channel activityISOJ:164563
Molecular FunctionGO:0005220inositol 1,4,5-trisphosphate-sensitive calcium-release channel activityIDAJ:121270
Molecular FunctionGO:0005220inositol 1,4,5-trisphosphate-sensitive calcium-release channel activityIDAJ:170219
Molecular FunctionGO:0005220inositol 1,4,5-trisphosphate-sensitive calcium-release channel activityISOJ:155856
Molecular FunctionGO:0005220inositol 1,4,5-trisphosphate-sensitive calcium-release channel activityIDAJ:100837
Molecular FunctionGO:0000822inositol hexakisphosphate bindingISOJ:155856
Molecular FunctionGO:0005216ion channel activityIEAJ:72247
Molecular FunctionGO:0035091phosphatidylinositol bindingIDAJ:121270
Molecular FunctionGO:0005515protein bindingIPIJ:105342
Molecular FunctionGO:0005515protein bindingIPIJ:166717
Molecular FunctionGO:0005515protein bindingIPIJ:203403
Cellular ComponentGO:0045177apical part of cellISOJ:155856
Cellular ComponentGO:0005903brush borderISOJ:155856
Cellular ComponentGO:0005737cytoplasmISOJ:155856
Cellular ComponentGO:0005737cytoplasmIDAJ:99797
Cellular ComponentGO:0005829cytosolISOJ:155856
Cellular ComponentGO:0030425dendriteISOJ:155856
Cellular ComponentGO:0005783endoplasmic reticulumISOJ:155856
Cellular ComponentGO:0005789endoplasmic reticulum membraneISOJ:164563
Cellular ComponentGO:0005789endoplasmic reticulum membraneISOJ:155856
Cellular ComponentGO:0005789endoplasmic reticulum membraneIDAJ:166717
Cellular ComponentGO:0016021integral component of membraneIEAJ:60000
Cellular ComponentGO:0005887integral component of plasma membraneISOJ:164563
Cellular ComponentGO:0016020membraneISOJ:164563
Cellular ComponentGO:0043209myelin sheathISOJ:155856
Cellular ComponentGO:0043025neuronal cell bodyISOJ:155856
Cellular ComponentGO:0005635nuclear envelopeISOJ:155856
Cellular ComponentGO:0005640nuclear outer membraneISOJ:155856
Cellular ComponentGO:0005730nucleolusIDAJ:99797
Cellular ComponentGO:0005654nucleoplasmIDAJ:99797
Cellular ComponentGO:0005634nucleusIDAJ:99797
Cellular ComponentGO:0048471perinuclear region of cytoplasmISOJ:155856
Cellular ComponentGO:0005886plasma membraneISOJ:164563
Cellular ComponentGO:0043235receptor complexISOJ:194542
Biological ProcessGO:0070588calcium ion transmembrane transportIEAJ:60000
Biological ProcessGO:0070588calcium ion transmembrane transportIEAJ:72247
Biological ProcessGO:0006816calcium ion transportIDAJ:100837
Biological ProcessGO:0006816calcium ion transportIDAJ:99797
Biological ProcessGO:0060402calcium ion transport into cytosolIDAJ:166717
Biological ProcessGO:0071320cellular response to cAMPISOJ:155856
Biological ProcessGO:0007186G-protein coupled receptor signaling pathwayISOJ:155856
Biological ProcessGO:0048016inositol phosphate-mediated signalingISOJ:164563
Biological ProcessGO:0048016inositol phosphate-mediated signalingISOJ:155856
Biological ProcessGO:0006811ion transportIEAJ:72247
Biological ProcessGO:0006811ion transportIEAJ:60000
Biological ProcessGO:0060291long-term synaptic potentiationIMPJ:136821
Biological ProcessGO:0007613memoryIMPJ:136821
Biological ProcessGO:0007204positive regulation of cytosolic calcium ion concentrationISOJ:155856
Biological ProcessGO:0051291protein heterooligomerizationISOJ:155856
Biological ProcessGO:0051260protein homooligomerizationISOJ:155856
Biological ProcessGO:0051592response to calcium ionISOJ:164563
Biological ProcessGO:0050913sensory perception of bitter tasteIMPJ:129007
Biological ProcessGO:0050916sensory perception of sweet tasteIMPJ:129007
Biological ProcessGO:0050917sensory perception of umami tasteIMPJ:129007
Biological ProcessGO:0055085transmembrane transportIEAJ:72247
Biological ProcessGO:0006810transportIEAJ:60000
GO:0005218IDAJ:170219


Gene Ontology Evidence Code Abbreviations:

Experimental:
EXP
Inferred from experiment
HMP
Inferred from high throughput mutant phenotype
HGI
Inferred from high throughput genetic interaction
HDA
Inferred from high throughput direct assay
HEP
Inferred from high throughput expression pattern
IDA
Inferred from direct assay
IEP
Inferred from expression pattern
IGI
Inferred from genetic interaction
IMP
Inferred from mutant phenotype
IPI
Inferred from physical interaction
Homology:
IAS
Inferred from ancestral sequence
IBA
Inferred from biological aspect of ancestor
IBD
Inferred from biological aspect of descendant
IKR
Inferred from key residues
IMR
Inferred from missing residues
IRD
Inferred from rapid divergence
ISA
Inferred from sequence alignment
ISM
Inferred from sequence model
ISO
Inferred from sequence orthology
ISS
Inferred from sequence or structural similarity
Automated:
IEA
Inferred from electronic annotation
RCA
Reviewed computational analysis
Other:
IC
Inferred by curator
NAS
Non-traceable author statement
ND
No biological data available
TAS
Traceable author statement


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
01/14/2020
MGI 6.14
The Jackson Laboratory